NXF1

UniProt Accession Q9UBU9 UniProt 🔗
Synonyms TAP
UniProt protein names Nuclear RNA export factor 1;
Tip-associated protein;
Tip-associating protein;
mRNA export factor TAP
Peak binding time (min) 50.3
Cluster III
Cluster membership (corr) 0.997
Peak broadness (1 / std of log2 intensities) 1.05
Cluster expected from GO V
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: miscellaneous, SAFE result: nuclear pore
RMSE (expected - observed) 0.88
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of NXF1 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q08211 DHX9 50.2 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 4 3
Q07955 SRSF1 41.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 3 4
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 3 3
Q96QD9 FYTTD1 75.0 V Nuclear speckles NMF result: no prediction, SAFE result: no prediction 3 2
Q16629 SRSF7 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 3
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q9HCD5 NCOA5 43.1 II Actin filaments;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q9BY77 POLDIP3 74.6 V Cytoplasmic bodies;Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 2
P78332 RBM6 38.1 II Cytoplasmic bodies;Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 2 2
O75683 SURF6 56.6 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
Q76FK4 NOL8 27.8 II Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 2 2
Q5SSJ5 HP1BP3 50.5 III Nuclear speckles NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 2
Q8NEY8 PPHLN1 35.3 II Golgi apparatus;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 2
O00267 SUPT5H 0.0 I Nucleoplasm NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 2
Q9H501 ESF1 45.4 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
Q8N684 CPSF7 36.9 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
P61978 HNRNPK 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q9H0D6 XRN2 41.9 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q9NY61 AATF 53.8 IV NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
O15234 CASC3 88.1 VI Nuclear membrane NMF result: no prediction, SAFE result: no prediction 2 2
Q9H2Y7 ZNF106 35.1 II Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
P17844 DDX5 40.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q9NTZ6 RBM12 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q96T37 RBM15 30.8 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 2 2
Q15397 PUM3 58.6 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
Q9NYF8 BCLAF1 37.5 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
O95232 LUC7L3 37.8 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 2 2
P52756 RBM5 33.5 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q9Y2W2 WBP11 39.9 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 2
Q15061 WDR43 34.7 II NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
Q14562 DHX8 46.2 III Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex II 2 2
Q9BUJ2 HNRNPUL1 42.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q53F19 NCBP3 77.1 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 2
Q8NDT2 RBM15B 45.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 1
P19338 NCL 27.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 1
P61326 MAGOH 70.2 V Nucleus NMF result: no prediction, SAFE result: no prediction 2 1
P12270 TPR 53.6 IV Nuclear membrane NMF result: no prediction, SAFE result: no prediction 1 2
P62826 RAN 44.7 III NMF result: no prediction, SAFE result: no prediction 1 2
Q8TCS8 PNPT1 53.6 IV Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
Q15637 SF1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14157 UBAP2L 212.4 VII Cytosol;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9P2N5 RBM27 49.2 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O43823 AKAP8 42.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P49756 RBM25 34.8 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O43670 ZNF207 29.7 II Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P18583 SON 43.3 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8N5F7 NKAP 47.0 III Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
P07814 EPRS 29.5 II Cytosol NMF result: actin cytoskeleton, cytosol, SAFE result: cell junction, plasma membrane 1 1
O60306 AQR 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q7KZ85 SUPT6H 0.0 I Cytosol;Nucleoplasm;Plasma membrane NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q8IY67 RAVER1 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P55854 SUMO3 48.3 III Nuclear bodies;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q5JTH9 RRP12 53.2 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q13595 TRA2A 42.2 II Nucleoli;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
Q9UPN6 SCAF8 0.0 I Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9NVU7 SDAD1 103.6 VI Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q8TEQ6 GEMIN5 42.4 III Cytosol;Nuclear bodies NMF result: no prediction, SAFE result: no prediction 1 1
Q9NZI8 IGF2BP1 143.9 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q92620 DHX38 54.2 IV Nucleus NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8IWZ8 SUGP1 32.9 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q15459 SF3A1 43.6 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P38159 RBMX 44.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O15347 HMGB3 46.3 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q00610 CLTC 33.4 II Cytosol;Mitotic spindle;Vesicles NMF result: actin cytoskeleton, cytosol, SAFE result: no prediction 1 1
Q9Y5S9 RBM8A 77.3 V Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q03701 CEBPZ 52.3 III Nucleus;Vesicles NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9Y2P8 RCL1 58.2 IV Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q8NE35 CPEB3 107.0 VI Intermediate filaments;Nuclear bodies;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9BQ67 GRWD1 42.3 II Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q52LJ0 FAM98B 62.5 IV Nucleoplasm;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q13148 TARDBP 49.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9NZB2 FAM120A 158.5 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P49761 CLK3 52.9 III Intermediate filaments;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q00325 SLC25A3 44.7 II Mitochondria NMF result: plasma membrane, SAFE result: - 1 1
Q9H7B2 RPF2 69.1 V Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: - 1 1
P46013 MKI67 62.1 V Nuclear bodies;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P27695 APEX1 53.4 III Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q8WUQ7 CACTIN 47.3 III Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8WUA2 PPIL4 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9HAV4 XPO5 45.6 III Nucleoplasm NMF result: nucleolus, SAFE result: no prediction 1 1
P52292 KPNA2 53.6 V Cytosol;Nucleoplasm NMF result: nucleoplasm, SAFE result: - 1 1
Q9Y4C8 RBM19 31.4 II Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q01130 SRSF2 41.6 II Cytosol;Nucleus NMF result: chromatin, SAFE result: - 1 1
O95639 CPSF4 36.9 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P20073 ANXA7 37.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9C0J8 WDR33 24.7 II Nucleoli fibrillar center;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q5T8P6 RBM26 53.9 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q01780 EXOSC10 58.1 IV Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8TF01 PNISR 45.7 III Cytosol;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q14011 CIRBP 41.6 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q14527 HLTF 49.9 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9Y3Y2 CHTOP 75.6 V Nuclear speckles NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P11021 HSPA5 48.9 III Cytosol NMF result: ER lumen, SAFE result: ER lumen 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9H089 LSG1 236.8 VII Cytosol;Nuclear bodies;Nucleus NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 1 1
Q9BYJ9 YTHDF1 222.1 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BZI7 UPF3B 64.9 V Cytosol;Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q99700 ATXN2 116.5 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9NRR4 DROSHA 45.3 III NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P24928 POLR2A 0.0 I Nucleoplasm NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
O60287 URB1 9.2 I Nucleoli fibrillar center NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
O75340 PDCD6 37.8 II Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P31942 HNRNPH3 39.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P08238 HSP90AB1 46.0 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
P09874 PARP1 45.3 II Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q16630 CPSF6 33.9 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P07910 HNRNPC 47.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P26599 PTBP1 46.5 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q86V81 ALYREF 71.2 V NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9GZR7 DDX24 58.0 IV Cytosol;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9GZR2 REXO4 52.4 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q14980 NUMA1 47.8 III Nucleoplasm NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q8N5C6 SRBD1 38.5 III Cytosol;Mitochondria NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
P62995 TRA2B 42.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9ULR0 ISY1 50.1 III Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q07065 CKAP4 40.2 II NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 1 1
Q96KR1 ZFR 46.6 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P49750 YLPM1 44.9 III Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9H000 MKRN2 65.9 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96EY7 PTCD3 77.4 V Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
P39748 FEN1 52.2 III Nucleoli;Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q14498 RBM39 30.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
Q8TA86 RP9 59.2 IV Cytosol;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q6PJT7 ZC3H14 65.7 IV Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
P52272 HNRNPM 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q7L2E3 DHX30 56.5 IV Cytosol;Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
Q9NUL3 STAU2 140.6 VII Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P68104 EEF1A1 42.8 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q9UGR2 ZC3H7B 80.7 VI NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P38919 EIF4A3 67.1 V Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 1
O15226 NKRF 47.5 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9P2E3 ZNFX1 233.0 VII Mitochondria NMF result: no prediction, SAFE result: no prediction 1 1
Q86XN8 MEX3D 81.7 VI NMF result: no prediction, SAFE result: no prediction 1 1
O95625 ZBTB11 62.2 III Nucleoplasm NMF result: nucleoplasm, SAFE result: no prediction 1 1
Q9UKM9 RALY 48.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q86XP3 DDX42 32.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q96EV2 RBM33 56.1 IV Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9BRP8 PYM1 247.2 VII Cell Junctions;Cytosol;Nucleoli;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - 1 1
P07900 HSP90AA1 48.1 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
O15260 SURF4 38.5 II NMF result: mitochondrial outer membrane, peroxisome, SAFE result: no prediction 1 1
Q9Y5B9 SUPT16H 12.0 I Nucleoli fibrillar center;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q99729 HNRNPAB 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14320 FAM50A 42.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P98175 RBM10 33.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1