CHTOP
| UniProt Accession | Q9Y3Y2 UniProt 🔗 |
|---|---|
| Synonyms | C1orf77, FOP, HT031, PP7704 |
| UniProt protein names | Chromatin target of PRMT1 protein;Friend of PRMT1 protein;Small arginine- and glycine-rich protein |
| Peak binding time (min) | 75.6 |
| Cluster | V |
| Cluster membership (corr) | 0.990 |
| Peak broadness (1 / std of log2 intensities) | 1.05 |
| Cluster expected from GO | V |
| Subcellular localization (Human Protein Atlas) | Nuclear speckles |
| Subcellular localization (Human Cell Map) | NMF result: chromatin, SAFE result: chromatin, nucleoplasm |
| RMSE (expected - observed) | 0.10 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of CHTOP in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q13838 | DDX39B | 67.1 | V | Nuclear speckles | NMF result: nuclear body, SAFE result: no prediction | 3 | 3 |
| Q96QD9 | FYTTD1 | 75.0 | V | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| Q96SB4 | SRPK1 | 52.0 | IV | Cytosol;Nucleus;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 1 | 1 |
| P27816 | MAP4 | 62.7 | V | Cytosol;Microtubules;Plasma membrane | NMF result: microtubule cytoskeleton, SAFE result: microtubule cytoskeleton | 1 | 1 |
| P38919 | EIF4A3 | 67.1 | V | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P61326 | MAGOH | 70.2 | V | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 1 | 1 |
| P98179 | RBM3 | 43.6 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P09012 | SNRPA | 44.9 | III | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P09429 | HMGB1 | 49.8 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q15646 | OASL | 104.1 | VI | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |
| P82979 | SARNP | 70.0 | V | Nuclear speckles | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q06787 | FMR1 | 176.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q9NYF8 | BCLAF1 | 37.5 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9HCE1 | MOV10 | 221.0 | VII | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |