SUPT5H

UniProt Accession O00267 UniProt 🔗
Synonyms SPT5, SPT5H
UniProt protein names Transcription elongation factor SPT5;
DRB sensitivity-inducing factor 160 kDa subunit;
DRB sensitivity-inducing factor large subunit;
Tat-cotransactivator 1 protein
Peak binding time (min) 0.0
Cluster I
Cluster membership (corr) 0.993
Peak broadness (1 / std of log2 intensities) 0.77
Cluster expected from GO I
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm
RMSE (expected - observed) 0.07
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of SUPT5H in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P24928 POLR2A 0.0 I Nucleoplasm NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 5 10
P30876 POLR2B 0.0 I Nucleoplasm NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 3 3
Q7KZ85 SUPT6H 0.0 I Cytosol;Nucleoplasm;Plasma membrane NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 3 3
Q5VT52 RPRD2 8.3 I Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: spliceosomal complex II 2 2
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 2 2
Q92541 RTF1 40.9 II Cytosol;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 2
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 2
Q92576 PHF3 0.0 I Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
P19338 NCL 27.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q15637 SF1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UPT8 ZC3H4 33.9 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
O95104 SCAF4 0.0 I Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
O60306 AQR 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q9BZJ0 CRNKL1 60.3 IV NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
P61978 HNRNPK 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96PV6 LENG8 50.0 III Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P27695 APEX1 53.4 III Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q99590 SCAF11 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9UK61 FAM208A 0.0 I Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q8IY67 RAVER1 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q16630 CPSF6 33.9 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P06733 ENO1 36.6 III Cytosol;Plasma membrane NMF result: miscellaneous, SAFE result: - 1 1
Q12905 ILF2 48.0 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P53999 SUB1 43.3 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P52597 HNRNPF 42.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q92620 DHX38 54.2 IV Nucleus NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9C0J8 WDR33 24.7 II Nucleoli fibrillar center;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O75534 CSDE1 122.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9UIG0 BAZ1B 44.3 II Nuclear bodies NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9H2Y7 ZNF106 35.1 II Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q53F19 NCBP3 77.1 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q96EV2 RBM33 56.1 IV Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96T58 SPEN 33.1 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P07900 HSP90AA1 48.1 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
O43719 HTATSF1 54.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9H7N4 SCAF1 31.3 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9UGU0 TCF20 39.4 II Nuclear bodies;Nucleoplasm NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9HCD5 NCOA5 43.1 II Actin filaments;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1