PNPT1
| UniProt Accession | Q8TCS8 UniProt 🔗 |
|---|---|
| Synonyms | PNPASE |
| UniProt protein names | Polyribonucleotide nucleotidyltransferase 1, mitochondrial;3'-5' RNA exonuclease OLD35;PNPase old-35;Polynucleotide phosphorylase 1;Polynucleotide phosphorylase-like protein |
| Peak binding time (min) | 53.6 |
| Cluster | IV |
| Cluster membership (corr) | 0.993 |
| Peak broadness (1 / std of log2 intensities) | 1.89 |
| Cluster expected from GO | IV |
| Subcellular localization (Human Protein Atlas) | Mitochondria |
| Subcellular localization (Human Cell Map) | NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix |
| RMSE (expected - observed) | 0.13 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of PNPT1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P19338 | NCL | 27.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9GZT3 | SLIRP | 71.4 | V | Mitochondria | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| P26599 | PTBP1 | 46.5 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P60842 | EIF4A1 | 96.8 | VI | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q7KZF4 | SND1 | 245.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P78563 | ADARB1 | 48.2 | III | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |