SFPQ


UniProt Accession P23246 UniProt 🔗
Synonyms PSF
UniProt protein names Splicing factor, proline- and glutamine-rich;
100 kDa DNA-pairing protein;
DNA-binding p52/p100 complex, 100 kDa subunit;
Polypyrimidine tract-binding protein-associated-splicing factor
Peak binding time (min) 45.2
Cluster II
Cluster membership (corr) 0.997
Peak broadness (1 / std of log2 intensities) 0.92
Cluster expected from GO II
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: paraspeckles
RMSE (expected - observed) 0.17
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of SFPQ in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q15233 NONO 42.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 6 11
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 3 4
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 3 3
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 3 2
P27695 APEX1 53.4 III Nucleus NMF result: no prediction, SAFE result: no prediction 3 2
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 3 2
P26599 PTBP1 46.5 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 3
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 2 2
O14776 TCERG1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 2 2
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 2
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
P09012 SNRPA 44.9 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
P43243 MATR3 47.9 III NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q15637 SF1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q08170 SRSF4 44.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q16629 SRSF7 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9P2N5 RBM27 49.2 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q96E39 RBMXL1 45.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P18583 SON 43.3 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q7RTV0 PHF5A 37.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
Q15459 SF3A1 43.6 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
O75400 PRPF40A 39.8 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q8WXF1 PSPC1 44.9 II Nucleoli fibrillar center;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q8ND56 LSM14A 138.4 VII Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9Y520 PRRC2C 147.3 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P31943 HNRNPH1 40.8 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9NR30 DDX21 0.0 I Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q92841 DDX17 39.2 II Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q07666 KHDRBS1 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q02880 TOP2B 50.4 III Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8IYB3 SRRM1 39.4 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q92879 CELF1 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9UQ35 SRRM2 42.5 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8NC51 SERBP1 213.4 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96CW1 AP2M1 45.0 III Plasma membrane NMF result: endosome, lysosome, SAFE result: endosome, lysosome 1 1
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9NWH9 SLTM 42.7 II Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13243 SRSF5 41.7 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P07910 HNRNPC 47.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P51991 HNRNPA3 43.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q86V81 ALYREF 71.2 V NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O60264 SMARCA5 34.8 II Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9BTC0 DIDO1 29.8 II Cytosol;Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O43719 HTATSF1 54.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P14866 HNRNPL 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P48634 PRRC2A 106.7 VI Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9HCD5 NCOA5 43.1 II Actin filaments;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
P49750 YLPM1 44.9 III Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9Y2W2 WBP11 39.9 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9Y5A9 YTHDF2 111.0 VI Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q7KZF4 SND1 245.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P52272 HNRNPM 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q7L2J0 MEPCE 53.8 III Cell Junctions;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9Y2W1 THRAP3 37.2 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9C0B0 UNK 88.4 VI Cytoplasmic bodies;Cytosol NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
P12270 TPR 53.6 IV Nuclear membrane NMF result: no prediction, SAFE result: no prediction 1 1
Q7Z2W4 ZC3HAV1 211.8 VII Cytosol;Golgi apparatus NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1