URB1
| UniProt Accession | O60287 UniProt 🔗 |
|---|---|
| Synonyms | C21orf108, KIAA0539, NOP254, NPA1 |
| UniProt protein names | Nucleolar pre-ribosomal-associated protein 1;Nucleolar protein 254 kDa;URB1 ribosome biogenesis 1 homolog |
| Peak binding time (min) | 9.2 |
| Cluster | I |
| Cluster membership (corr) | 0.996 |
| Peak broadness (1 / std of log2 intensities) | 0.88 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Nucleoli fibrillar center |
| Subcellular localization (Human Cell Map) | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm |
| RMSE (expected - observed) | 0.36 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of URB1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P06748 | NPM1 | 56.1 | IV | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| P42696 | RBM34 | 41.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| Q96ME7 | ZNF512 | 45.2 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| O43159 | RRP8 | 43.2 | II | Cytosol;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9BWF3 | RBM4 | 40.3 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9P031 | CCDC59 | 42.4 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q76FK4 | NOL8 | 27.8 | II | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9BQ67 | GRWD1 | 42.3 | II | Nucleoli;Nucleus | NMF result: plasma membrane, SAFE result: - | 1 | 1 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |