TPR

UniProt Accession P12270 UniProt 🔗
Synonyms
UniProt protein names Nucleoprotein TPR;
Megator;
NPC-associated intranuclear protein;
Translocated promoter region protein
Peak binding time (min) 53.6
Cluster IV
Cluster membership (corr) 0.982
Peak broadness (1 / std of log2 intensities) 1.87
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Nuclear membrane
Subcellular localization (Human Cell Map) NMF result: no prediction, SAFE result: no prediction
RMSE (expected - observed) 0.14
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of TPR in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 2
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 2 2
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 1 2
Q05519 SRSF11 52.0 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P62826 RAN 44.7 III NMF result: no prediction, SAFE result: no prediction 1 1
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q92499 DDX1 74.7 V Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O00422 SAP18 63.4 IV Cytosol;Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P62314 SNRPD1 54.6 IV NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 1
Q5JTH9 RRP12 53.2 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13243 SRSF5 41.7 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
O96028 NSD2 41.7 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q13123 IK 51.9 IV Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9BWF3 RBM4 40.3 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q14011 CIRBP 41.6 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9Y3B4 SF3B6 36.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1