PNISR
| UniProt Accession | Q8TF01 UniProt 🔗 |
|---|---|
| Synonyms | C6orf111, HSPC261, HSPC306, SFRS18, SRRP130 |
| UniProt protein names | Arginine/serine-rich protein PNISR;PNN-interacting serine/arginine-rich protein;SR-related protein;SR-rich protein;Serine/arginine-rich-splicing regulatory protein 130;Splicing factor, arginine/serine-rich 130;Splicing factor, arginine/serine-rich 18 |
| Peak binding time (min) | 45.7 |
| Cluster | III |
| Cluster membership (corr) | 0.994 |
| Peak broadness (1 / std of log2 intensities) | 1.54 |
| Cluster expected from GO | V |
| Subcellular localization (Human Protein Atlas) | Cytosol;Nuclear speckles |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus |
| RMSE (expected - observed) | 0.78 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of PNISR in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q9H307 | PNN | 64.6 | IV | Nuclear speckles | NMF result: nuclear body, SAFE result: spliceosomal complex II | 2 | 1 |
| Q05519 | SRSF11 | 52.0 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9HCE1 | MOV10 | 221.0 | VII | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| Q99459 | CDC5L | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q14498 | RBM39 | 30.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |