UPF3B
| UniProt Accession | Q9BZI7 UniProt 🔗 |
|---|---|
| Synonyms | RENT3B, UPF3X |
| UniProt protein names | Regulator of nonsense transcripts 3B;Nonsense mRNA reducing factor 3B;Up-frameshift suppressor 3 homolog B;Up-frameshift suppressor 3 homolog on chromosome X |
| Peak binding time (min) | 64.9 |
| Cluster | V |
| Cluster membership (corr) | 0.985 |
| Peak broadness (1 / std of log2 intensities) | 2.07 |
| Cluster expected from GO | V |
| Subcellular localization (Human Protein Atlas) | Cytosol;Nucleoli;Nucleus |
| Subcellular localization (Human Cell Map) | NMF result: plasma membrane, SAFE result: - |
| RMSE (expected - observed) | 0.23 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of UPF3B in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P38919 | EIF4A3 | 67.1 | V | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 3 | 3 |
| Q92900 | UPF1 | 158.9 | VII | Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 2 | 8 |
| Q9Y5S9 | RBM8A | 77.3 | V | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 2 | 3 |
| Q15287 | RNPS1 | 58.0 | IV | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 2 | 2 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 2 | 2 |
| O15234 | CASC3 | 88.1 | VI | Nuclear membrane | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| Q9Y2W2 | WBP11 | 39.9 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| O43290 | SART1 | 39.6 | II | Golgi apparatus;Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q5TC82 | RC3H1 | 62.0 | IV | Cytosol;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q8N5F7 | NKAP | 47.0 | III | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: spliceosomal complex II | 1 | 1 |
| P11388 | TOP2A | 49.6 | III | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q8NC51 | SERBP1 | 213.4 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| P51114 | FXR1 | 172.6 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P61326 | MAGOH | 70.2 | V | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q9BRP8 | PYM1 | 247.2 | VII | Cell Junctions;Cytosol;Nucleoli;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - | 1 | 1 |
| Q15365 | PCBP1 | 48.6 | III | Cytoplasmic bodies;Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |