HSP90AB1
| UniProt Accession | P08238 UniProt 🔗 |
|---|---|
| Synonyms | HSP90B, HSPC2, HSPCB |
| UniProt protein names | Heat shock protein HSP 90-beta;Heat shock 84 kDa |
| Peak binding time (min) | 46.0 |
| Cluster | III |
| Cluster membership (corr) | 0.984 |
| Peak broadness (1 / std of log2 intensities) | 1.55 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Cytosol |
| Subcellular localization (Human Cell Map) | NMF result: no prediction, SAFE result: no prediction |
| RMSE (expected - observed) | 0.16 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of HSP90AB1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P07900 | HSP90AA1 | 48.1 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 4 | 8 |
| Q9UHD1 | CHORDC1 | 39.0 | III | Cytosol | NMF result: miscellaneous, SAFE result: - | 3 | 4 |
| P11142 | HSPA8 | 45.1 | III | Nucleoplasm;Vesicles | NMF result: miscellaneous, SAFE result: no prediction | 3 | 3 |
| P33992 | MCM5 | 42.8 | III | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 3 |
| P04406 | GAPDH | 42.0 | III | Cytosol;Plasma membrane | NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - | 2 | 2 |
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 |
| Q14004 | CDK13 | 37.1 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 2 |
| Q15365 | PCBP1 | 48.6 | III | Cytoplasmic bodies;Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| P11021 | HSPA5 | 48.9 | III | Cytosol | NMF result: ER lumen, SAFE result: ER lumen | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| P07437 | TUBB | 34.3 | II | Microtubules | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P49761 | CLK3 | 52.9 | III | Intermediate filaments;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q7KZF4 | SND1 | 245.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P00338 | LDHA | 44.4 | III | Cytosol;Vesicles | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
| P62314 | SNRPD1 | 54.6 | IV | NMF result: nuclear body, SAFE result: spliceosomal complex I | 1 | 1 | |
| P06748 | NPM1 | 56.1 | IV | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q99459 | CDC5L | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q13573 | SNW1 | 51.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 1 | 1 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P52292 | KPNA2 | 53.6 | V | Cytosol;Nucleoplasm | NMF result: nucleoplasm, SAFE result: - | 1 | 1 |
| P06733 | ENO1 | 36.6 | III | Cytosol;Plasma membrane | NMF result: miscellaneous, SAFE result: - | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P17987 | TCP1 | 45.1 | III | NMF result: miscellaneous, SAFE result: chaperonin-containing T-complex, prefoldin complex | 1 | 1 | |
| P14618 | PKM | 44.0 | III | Cytosol | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
| P60842 | EIF4A1 | 96.8 | VI | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9GZR7 | DDX24 | 58.0 | IV | Cytosol;Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| O15372 | EIF3H | 64.3 | IV | Cytosol | NMF result: centrosome, SAFE result: - | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q14980 | NUMA1 | 47.8 | III | Nucleoplasm | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9C0B0 | UNK | 88.4 | VI | Cytoplasmic bodies;Cytosol | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| Q9BQ67 | GRWD1 | 42.3 | II | Nucleoli;Nucleus | NMF result: plasma membrane, SAFE result: - | 1 | 1 |
| Q9H9G7 | AGO3 | 91.6 | VI | Cytoplasmic bodies;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |