CLTC
| UniProt Accession | Q00610 UniProt 🔗 |
|---|---|
| Synonyms | CLH17, CLTCL2, KIAA0034 |
| UniProt protein names | Clathrin heavy chain 1;Clathrin heavy chain on chromosome 17 |
| Peak binding time (min) | 33.4 |
| Cluster | II |
| Cluster membership (corr) | 0.988 |
| Peak broadness (1 / std of log2 intensities) | 2.24 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Cytosol;Mitotic spindle;Vesicles |
| Subcellular localization (Human Cell Map) | NMF result: actin cytoskeleton, cytosol, SAFE result: no prediction |
| RMSE (expected - observed) | 0.27 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of CLTC in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P11142 | HSPA8 | 45.1 | III | Nucleoplasm;Vesicles | NMF result: miscellaneous, SAFE result: no prediction | 2 | 2 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 2 | 1 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 2 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 2 |
| Q96CW1 | AP2M1 | 45.0 | III | Plasma membrane | NMF result: endosome, lysosome, SAFE result: endosome, lysosome | 1 | 2 |
| Q9NZ01 | TECR | 43.4 | III | Endoplasmic reticulum | NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - | 1 | 1 |
| O14617 | AP3D1 | 43.2 | III | Cytosol | NMF result: endosome, lysosome, SAFE result: endosome, lysosome | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q00325 | SLC25A3 | 44.7 | II | Mitochondria | NMF result: plasma membrane, SAFE result: - | 1 | 1 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P06748 | NPM1 | 56.1 | IV | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q96PK6 | RBM14 | 42.9 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 1 | 1 |
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q92620 | DHX38 | 54.2 | IV | Nucleus | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q8N684 | CPSF7 | 36.9 | II | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9C0B0 | UNK | 88.4 | VI | Cytoplasmic bodies;Cytosol | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| Q9BQ67 | GRWD1 | 42.3 | II | Nucleoli;Nucleus | NMF result: plasma membrane, SAFE result: - | 1 | 1 |