HMGB3
| UniProt Accession | O15347 UniProt 🔗 |
|---|---|
| Synonyms | HMG2A, HMG4 |
| UniProt protein names | High mobility group protein B3;High mobility group protein 2a;High mobility group protein 4 |
| Peak binding time (min) | 46.3 |
| Cluster | III |
| Cluster membership (corr) | 0.977 |
| Peak broadness (1 / std of log2 intensities) | 2.53 |
| Cluster expected from GO | IV |
| Subcellular localization (Human Protein Atlas) | Nucleoli;Nucleus |
| Subcellular localization (Human Cell Map) | NMF result: chromatin, SAFE result: chromatin, nucleoplasm |
| RMSE (expected - observed) | 0.37 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of HMGB3 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q13283 | G3BP1 | 220.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P09429 | HMGB1 | 49.8 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9NPD3 | EXOSC4 | 57.8 | IV | Cytosol;Intermediate filaments | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9HCE1 | MOV10 | 221.0 | VII | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| Q9Y5B9 | SUPT16H | 12.0 | I | Nucleoli fibrillar center;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P17096 | HMGA1 | 45.8 | III | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |
| Q08945 | SSRP1 | 0.0 | I | Cytosol;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |