HNRNPK
| UniProt Accession | P61978 UniProt 🔗 |
|---|---|
| Synonyms | HNRPK |
| UniProt protein names | Heterogeneous nuclear ribonucleoprotein K;Transformation up-regulated nuclear protein |
| Peak binding time (min) | 42.6 |
| Cluster | II |
| Cluster membership (corr) | 0.999 |
| Peak broadness (1 / std of log2 intensities) | 0.91 |
| Cluster expected from GO | II |
| Subcellular localization (Human Protein Atlas) | Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: paraspeckles |
| RMSE (expected - observed) | 0.11 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of HNRNPK in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P11940 | PABPC1 | 124.3 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 3 | 3 |
| Q07666 | KHDRBS1 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 3 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 3 | 3 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 3 | 3 |
| P26599 | PTBP1 | 46.5 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 3 |
| P14866 | HNRNPL | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 3 |
| Q14103 | HNRNPD | 43.1 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 3 |
| Q92499 | DDX1 | 74.7 | V | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 3 | 1 |
| P43243 | MATR3 | 47.9 | III | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 6 | |
| P38159 | RBMX | 44.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 6 |
| Q96PU8 | QKI | 47.1 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 5 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 5 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| Q12906 | ILF3 | 48.8 | III | Mitochondria;Nucleoli;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
| Q13151 | HNRNPA0 | 43.7 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 2 | 2 |
| P31943 | HNRNPH1 | 40.8 | II | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
| P09429 | HMGB1 | 49.8 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 2 | 2 |
| O60506 | SYNCRIP | 71.4 | V | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles | 2 | 2 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 2 | 2 |
| Q15365 | PCBP1 | 48.6 | III | Cytoplasmic bodies;Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| Q15366 | PCBP2 | 48.9 | III | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 2 | 1 |
| Q14011 | CIRBP | 41.6 | II | Nucleoli;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 5 |
| Q8WWY3 | PRPF31 | 46.6 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 4 |
| Q8WVV9 | HNRNPLL | 43.8 | II | Cytosol;Mitochondria;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 4 |
| Q96MU7 | YTHDC1 | 54.8 | IV | Nucleoplasm;Plasma membrane | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 3 |
| Q9BTD8 | RBM42 | 40.1 | II | Cytosol;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 3 |
| P09012 | SNRPA | 44.9 | III | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 3 |
| Q00839 | HNRNPU | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 |
| P19338 | NCL | 27.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| Q9Y580 | RBM7 | 36.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 |
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 |
| P98179 | RBM3 | 43.6 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q15637 | SF1 | 40.9 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P62314 | SNRPD1 | 54.6 | IV | NMF result: nuclear body, SAFE result: spliceosomal complex I | 1 | 1 | |
| Q13573 | SNW1 | 51.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q15428 | SF3A2 | 31.3 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O43251 | RBFOX2 | 45.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q92804 | TAF15 | 35.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9GZT3 | SLIRP | 71.4 | V | Mitochondria | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q08211 | DHX9 | 50.2 | III | Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |
| Q15459 | SF3A1 | 43.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| O75400 | PRPF40A | 39.8 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P22626 | HNRNPA2B1 | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P84103 | SRSF3 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| Q13148 | TARDBP | 49.3 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| O60293 | ZFC3H1 | 51.3 | III | Intermediate filaments;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P27695 | APEX1 | 53.4 | III | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q99459 | CDC5L | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P61326 | MAGOH | 70.2 | V | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9NY93 | DDX56 | 51.2 | III | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 | |
| P06733 | ENO1 | 36.6 | III | Cytosol;Plasma membrane | NMF result: miscellaneous, SAFE result: - | 1 | 1 |
| O96028 | NSD2 | 41.7 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9BWF3 | RBM4 | 40.3 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q7Z2T5 | TRMT1L | 57.1 | III | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q92841 | DDX17 | 39.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O00267 | SUPT5H | 0.0 | I | Nucleoplasm | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O14776 | TCERG1 | 40.9 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q92879 | CELF1 | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q5TC82 | RC3H1 | 62.0 | IV | Cytosol;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q9UQ35 | SRRM2 | 42.5 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q15393 | SF3B3 | 45.7 | II | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9BXP5 | SRRT | 44.7 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| Q07955 | SRSF1 | 41.6 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P11387 | TOP1 | 48.2 | III | Nucleoli fibrillar center;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9H0D6 | XRN2 | 41.9 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P14618 | PKM | 44.0 | III | Cytosol | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
| P51991 | HNRNPA3 | 43.2 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9BTC0 | DIDO1 | 29.8 | II | Cytosol;Nucleoplasm;Vesicles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P55795 | HNRNPH2 | 36.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O75533 | SF3B1 | 40.9 | II | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q05519 | SRSF11 | 52.0 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P17844 | DDX5 | 40.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9BQ52 | ELAC2 | 60.6 | III | Nucleoplasm | NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix | 1 | 1 |
| P67809 | YBX1 | 148.5 | VII | Cytosol;Vesicles | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q9BZZ5 | API5 | 69.0 | V | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9UQ80 | PA2G4 | 53.8 | IV | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q9BTL3 | RAMAC | 30.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P52272 | HNRNPM | 46.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9NR56 | MBNL1 | 49.5 | III | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q96PK6 | RBM14 | 42.9 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P68104 | EEF1A1 | 42.8 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P38919 | EIF4A3 | 67.1 | V | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P52597 | HNRNPF | 42.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q96QC0 | PPP1R10 | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9UKM9 | RALY | 48.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q8IX12 | CCAR1 | 35.1 | II | Golgi apparatus;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O43143 | DHX15 | 35.8 | II | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P07900 | HSP90AA1 | 48.1 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P98175 | RBM10 | 33.0 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| O43390 | HNRNPR | 48.0 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |