CPSF7

UniProt Accession Q8N684 UniProt 🔗
Synonyms
UniProt protein names Cleavage and polyadenylation specificity factor subunit 7;
Cleavage and polyadenylation specificity factor 59 kDa subunit;
Cleavage factor Im complex 59 kDa subunit;
Pre-mRNA cleavage factor Im 59 kDa subunit
Peak binding time (min) 36.9
Cluster II
Cluster membership (corr) 0.999
Peak broadness (1 / std of log2 intensities) 0.96
Cluster expected from GO I
Subcellular localization (Human Protein Atlas) Cytosol;Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: paraspeckles
RMSE (expected - observed) 0.16
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of CPSF7 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
O43809 NUDT21 41.6 II Nuclear bodies NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 3 5
Q16630 CPSF6 33.9 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 3
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 2 2
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
P98175 RBM10 33.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 2
Q14157 UBAP2L 212.4 VII Cytosol;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q92879 CELF1 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q92945 KHSRP 37.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
Q13283 G3BP1 220.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96PV6 LENG8 50.0 III Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P06733 ENO1 36.6 III Cytosol;Plasma membrane NMF result: miscellaneous, SAFE result: - 1 1
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P52597 HNRNPF 42.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96I24 FUBP3 51.8 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P11142 HSPA8 45.1 III Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 1
Q00610 CLTC 33.4 II Cytosol;Mitotic spindle;Vesicles NMF result: actin cytoskeleton, cytosol, SAFE result: no prediction 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q9HBE1 PATZ1 39.3 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9NQ29 LUC7L 43.6 II Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1