NCL


UniProt Accession P19338 UniProt 🔗
Synonyms
UniProt protein names Nucleolin;
Protein C23
Peak binding time (min) 27.1
Cluster II
Cluster membership (corr) 0.993
Peak broadness (1 / std of log2 intensities) 0.95
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Nucleoli;Nucleus
Subcellular localization (Human Cell Map) NMF result: nucleolus, SAFE result: splicing speckles, nucleolus
RMSE (expected - observed) 0.32
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of NCL in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 4 6
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 3 4
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 3 3
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 3 2
Q9UQ80 PA2G4 53.8 IV Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 3
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q08211 DHX9 50.2 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
P05455 SSB 45.1 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 2
Q01780 EXOSC10 58.1 IV Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 2 1
Q7Z2W4 ZC3HAV1 211.8 VII Cytosol;Golgi apparatus NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 2 1
Q86V81 ALYREF 71.2 V NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 1
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 2 1
P27695 APEX1 53.4 III Nucleus NMF result: no prediction, SAFE result: no prediction 2 1
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 2
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 2
Q9BQG0 MYBBP1A 54.4 IV Nucleoli;Vesicles NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 2
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
Q9Y262 EIF3L 193.3 VII Nucleoli;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 2
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 2
P61978 HNRNPK 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q8TCS8 PNPT1 53.6 IV Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
P42285 MTREX 73.4 V Nucleus NMF result: chromatin, SAFE result: - 1 1
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q06265 EXOSC9 54.5 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P30876 POLR2B 0.0 I Nucleoplasm NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
P62314 SNRPD1 54.6 IV NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q7RTV0 PHF5A 37.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q7KZ85 SUPT6H 0.0 I Cytosol;Nucleoplasm;Plasma membrane NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
Q15427 SF3B4 38.3 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q9H0A0 NAT10 55.7 IV Midbody;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9BZE4 GTPBP4 76.2 V Nuclear membrane;Nucleoli NMF result: nucleolus, SAFE result: no prediction 1 1
Q9NZI8 IGF2BP1 143.9 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q13610 PWP1 44.9 II Golgi apparatus;Nucleoli NMF result: no prediction, SAFE result: no prediction 1 1
Q8TDN6 BRIX1 58.0 IV Nucleoli NMF result: miscellaneous, SAFE result: no prediction 1 1
Q9NZM5 NOP53 89.6 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9NVP1 DDX18 49.1 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9Y2P8 RCL1 58.2 IV Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9BQ67 GRWD1 42.3 II Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
Q13148 TARDBP 49.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9NPD3 EXOSC4 57.8 IV Cytosol;Intermediate filaments NMF result: no prediction, SAFE result: no prediction 1 1
Q9NX58 LYAR 25.6 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q96QD9 FYTTD1 75.0 V Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q9H7B2 RPF2 69.1 V Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: - 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P31943 HNRNPH1 40.8 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9NVV4 MTPAP 50.7 III Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9NR30 DDX21 0.0 I Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P09429 HMGB1 49.8 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9BTD8 RBM42 40.1 II Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
O96028 NSD2 41.7 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O75940 SMNDC1 36.3 II Nuclear bodies;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O75821 EIF3G 105.9 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BVP2 GNL3 68.1 V Nuclear bodies;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
O00267 SUPT5H 0.0 I Nucleoplasm NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
O75643 SNRNP200 42.7 II Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P17096 HMGA1 45.8 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q8IYB3 SRRM1 39.4 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O43395 PRPF3 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P51532 SMARCA4 51.3 III Nucleoplasm NMF result: nucleoplasm, SAFE result: Arp2/3 protein complex 1 1
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q13243 SRSF5 41.7 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P26599 PTBP1 46.5 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9GZR7 DDX24 58.0 IV Cytosol;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O60264 SMARCA5 34.8 II Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q06787 FMR1 176.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P11940 PABPC1 124.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P67809 YBX1 148.5 VII Cytosol;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9BZZ5 API5 69.0 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O15371 EIF3D 208.1 VII Cytosol NMF result: miscellaneous, SAFE result: - 1 1
Q14498 RBM39 30.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
Q7L2E3 DHX30 56.5 IV Cytosol;Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
Q9BRJ6 C7orf50 51.1 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9BQ39 DDX50 23.3 II Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
O15042 U2SURP 33.1 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q7L2J0 MEPCE 53.8 III Cell Junctions;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q92522 H1FX 41.6 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: no prediction 1 1
Q12905 ILF2 48.0 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q08J23 NSUN2 52.7 III Nucleus NMF result: miscellaneous, SAFE result: - 1 1
P37108 SRP14 45.6 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9H0S4 DDX47 49.7 III Nucleoli NMF result: miscellaneous, SAFE result: - 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P07900 HSP90AA1 48.1 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O15446 CD3EAP 0.0 I Mitochondria;Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: no prediction 1 1
Q9C0B0 UNK 88.4 VI Cytoplasmic bodies;Cytosol NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
Q15061 WDR43 34.7 II NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1