DHX8

UniProt Accession Q14562 UniProt 🔗
Synonyms DDX8
UniProt protein names ATP-dependent RNA helicase DHX8;
DEAH box protein 8;
RNA helicase HRH1
Peak binding time (min) 46.2
Cluster III
Cluster membership (corr) 0.995
Peak broadness (1 / std of log2 intensities) 0.91
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Nuclear bodies;Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: spliceosomal complex II
RMSE (expected - observed) 0.14
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of DHX8 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q9ULR0 ISY1 50.1 III Nuclear speckles NMF result: no prediction, SAFE result: no prediction 3 3
Q9BZJ0 CRNKL1 60.3 IV NMF result: nuclear body, SAFE result: spliceosomal complex II 2 3
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 3
Q9Y388 RBMX2 39.8 II Nuclear membrane;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 2 2
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 2 2
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q8N5F7 NKAP 47.0 III Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex II 2 1
Q8IWX8 CHERP 23.2 II NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 3
Q8WUQ7 CACTIN 47.3 III Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
O60306 AQR 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 2
Q9H307 PNN 64.6 IV Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q9Y580 RBM7 36.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q8NC51 SERBP1 213.4 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q7RTV0 PHF5A 37.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P46087 NOP2 57.6 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P55081 MFAP1 43.9 II NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P06733 ENO1 36.6 III Cytosol;Plasma membrane NMF result: miscellaneous, SAFE result: - 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9H0D6 XRN2 41.9 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
O75400 PRPF40A 39.8 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9NW13 RBM28 49.3 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1