SRSF2

UniProt Accession Q01130 UniProt 🔗
Synonyms SFRS2
UniProt protein names Serine/arginine-rich splicing factor 2;
Protein PR264;
Splicing component, 35 kDa;
Splicing factor SC35;
Splicing factor, arginine/serine-rich 2
Peak binding time (min) 41.6
Cluster II
Cluster membership (corr) 1.000
Peak broadness (1 / std of log2 intensities) 0.97
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Cytosol;Nucleus
Subcellular localization (Human Cell Map) NMF result: chromatin, SAFE result: -
RMSE (expected - observed) 0.10
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of SRSF2 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 2 2
Q07955 SRSF1 41.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
Q05519 SRSF11 52.0 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q08170 SRSF4 44.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 1 1
P35659 DEK 45.5 II Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O14979 HNRNPDL 43.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13242 SRSF9 44.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P24928 POLR2A 0.0 I Nucleoplasm NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P38919 EIF4A3 67.1 V Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15428 SF3A2 31.3 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P61326 MAGOH 70.2 V Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P53999 SUB1 43.3 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q86V81 ALYREF 71.2 V NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P62995 TRA2B 42.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q8IYB3 SRRM1 39.4 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1