HLTF
| UniProt Accession | Q14527 UniProt 🔗 |
|---|---|
| Synonyms | HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1 |
| UniProt protein names | Helicase-like transcription factor;DNA-binding protein/plasminogen activator inhibitor 1 regulator;HIP116;RING finger protein 80;RING-type E3 ubiquitin transferase HLTF;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3;Sucrose nonfermenting protein 2-like 3 |
| Peak binding time (min) | 49.9 |
| Cluster | III |
| Cluster membership (corr) | 0.996 |
| Peak broadness (1 / std of log2 intensities) | 1.13 |
| Cluster expected from GO | IV |
| Subcellular localization (Human Protein Atlas) | Nucleus |
| Subcellular localization (Human Cell Map) | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm |
| RMSE (expected - observed) | 0.39 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of HLTF in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 3 |
| P11142 | HSPA8 | 45.1 | III | Nucleoplasm;Vesicles | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| Q99459 | CDC5L | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q13573 | SNW1 | 51.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P29558 | RBMS1 | 107.1 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q8TAD8 | SNIP1 | 40.9 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |