MKI67

UniProt Accession P46013 UniProt 🔗
Synonyms
UniProt protein names Proliferation marker protein Ki-67;
Antigen identified by monoclonal antibody Ki-67
Peak binding time (min) 62.1
Cluster V
Cluster membership (corr) 0.972
Peak broadness (1 / std of log2 intensities) 1.61
Cluster expected from GO IV
Subcellular localization (Human Protein Atlas) Nuclear bodies;Nucleoli;Nucleus
Subcellular localization (Human Cell Map) NMF result: nucleolus, SAFE result: chromatin, nucleoplasm
RMSE (expected - observed) 0.11
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of MKI67 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q13283 G3BP1 220.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 2
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 2
P63244 RACK1 43.3 III Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q08170 SRSF4 44.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q8NDF8 TENT4B 47.1 III NMF result: no prediction, SAFE result: no prediction 1 1
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q96E39 RBMXL1 45.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q5QJE6 DNTTIP2 53.9 IV Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q06265 EXOSC9 54.5 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q92945 KHSRP 37.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P18583 SON 43.3 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9NWT1 PAK1IP1 49.1 III Nucleoli;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q8WTT2 NOC3L 66.5 V Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q6UN15 FIP1L1 19.3 I Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9NVU7 SDAD1 103.6 VI Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q8TDD1 DDX54 67.3 V Golgi apparatus;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9BZE4 GTPBP4 76.2 V Nuclear membrane;Nucleoli NMF result: nucleolus, SAFE result: no prediction 1 1
Q15361 TTF1 26.0 II Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: no prediction 1 1
Q1ED39 KNOP1 38.4 II Cytosol;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9NVN8 GNL3L 135.5 VI Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q8TDN6 BRIX1 58.0 IV Nucleoli NMF result: miscellaneous, SAFE result: no prediction 1 1
Q14331 FRG1 42.8 III NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9NZM5 NOP53 89.6 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
Q9UBU9 NXF1 50.3 III Nucleoplasm NMF result: miscellaneous, SAFE result: nuclear pore 1 1
Q9NX58 LYAR 25.6 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9H2U1 DHX36 50.1 III Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9H7B2 RPF2 69.1 V Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: - 1 1
P00338 LDHA 44.4 III Cytosol;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 1
Q9H6F5 CCDC86 98.8 VI Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9UIF9 BAZ2A 49.2 III Nuclear speckles NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q96PV6 LENG8 50.0 III Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q99590 SCAF11 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P12236 SLC25A6 45.8 III Mitochondria NMF result: mitochondrial matrix, SAFE result: no prediction 1 1
Q9BYG3 NIFK 58.9 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9UH17 APOBEC3B 44.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9NY93 DDX56 51.2 III NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O15381 NVL 49.2 III Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9H9L3 ISG20L2 47.7 III Nucleoplasm NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O96028 NSD2 41.7 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9UHA3 RSL24D1 62.1 IV Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P17987 TCP1 45.1 III NMF result: miscellaneous, SAFE result: chaperonin-containing T-complex, prefoldin complex 1 1
Q96I24 FUBP3 51.8 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
Q14004 CDK13 37.1 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9H2Y7 ZNF106 35.1 II Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O15372 EIF3H 64.3 IV Cytosol NMF result: centrosome, SAFE result: - 1 1
Q9BVP2 GNL3 68.1 V Nuclear bodies;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8NEY8 PPHLN1 35.3 II Golgi apparatus;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9UKV3 ACIN1 60.5 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q96GQ7 DDX27 62.3 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O75643 SNRNP200 42.7 II Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q96QR8 PURB 143.9 VII Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P42696 RBM34 41.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
O43395 PRPF3 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9BYJ9 YTHDF1 222.1 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9H8H2 DDX31 40.8 II Golgi apparatus;Nucleoli;Vesicles NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9BRL6 SRSF8 42.6 II Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13243 SRSF5 41.7 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9H0D6 XRN2 41.9 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14444 CAPRIN1 229.7 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q7Z739 YTHDF3 111.3 VI Cytosol;Nuclear membrane;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9GZR7 DDX24 58.0 IV Cytosol;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P16989 YBX3 137.7 VII Cytosol NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q06787 FMR1 176.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BTC0 DIDO1 29.8 II Cytosol;Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q53F19 NCBP3 77.1 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q96T58 SPEN 33.1 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P49750 YLPM1 44.9 III Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q6NZY4 ZCCHC8 40.2 II Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 1
Q15397 PUM3 58.6 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9H307 PNN 64.6 IV Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q13247 SRSF6 45.9 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q8N3Z6 ZCCHC7 46.0 III Cytosol;Nucleoli NMF result: no prediction, SAFE result: no prediction 1 1
Q9Y5A9 YTHDF2 111.0 VI Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96EY7 PTCD3 77.4 V Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
O15371 EIF3D 208.1 VII Cytosol NMF result: miscellaneous, SAFE result: - 1 1
Q6PJT7 ZC3H14 65.7 IV Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9NUL3 STAU2 140.6 VII Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9BRJ6 C7orf50 51.1 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q1KMD3 HNRNPUL2 42.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q8WUB8 PHF10 48.0 III Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9BQ39 DDX50 23.3 II Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 1
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9P275 USP36 42.4 II Nuclear speckles;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O15226 NKRF 47.5 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q6PK04 CCDC137 59.7 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q96AE4 FUBP1 36.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13123 IK 51.9 IV Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q12874 SF3A3 37.2 II Nucleoplasm NMF result: chromatin, SAFE result: splicing speckles, nucleolus 1 1
Q13428 TCOF1 0.0 I Nucleoli fibrillar center NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q00577 PURA 171.5 VII NMF result: no prediction, SAFE result: no prediction 1 1
Q13823 GNL2 111.9 VI Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9NV06 DCAF13 49.2 III Cell Junctions;Centrosome;Cytosol;Nucleoli;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: splicing speckles, nucleolus 1 1