CLK3
| UniProt Accession | P49761 UniProt 🔗 |
|---|---|
| Synonyms | |
| UniProt protein names | Dual specificity protein kinase CLK3;CDC-like kinase 3 |
| Peak binding time (min) | 52.9 |
| Cluster | III |
| Cluster membership (corr) | 0.977 |
| Peak broadness (1 / std of log2 intensities) | 1.59 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Intermediate filaments;Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: no prediction, SAFE result: no prediction |
| RMSE (expected - observed) | 0.24 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of CLK3 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q8TAD8 | SNIP1 | 40.9 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 3 |
| P62995 | TRA2B | 42.0 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| P07900 | HSP90AA1 | 48.1 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| Q9BRL6 | SRSF8 | 42.6 | II | Cytosol;Nucleus | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| O75494 | SRSF10 | 46.3 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 2 | 2 |
| Q13595 | TRA2A | 42.2 | II | Nucleoli;Vesicles | NMF result: no prediction, SAFE result: no prediction | 1 | 3 |
| Q9UKJ3 | GPATCH8 | 61.2 | IV | Mitochondria;Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| Q9NQ29 | LUC7L | 43.6 | II | Mitochondria;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q9Y383 | LUC7L2 | 29.7 | II | Nucleus | NMF result: ER lumen, SAFE result: - | 1 | 2 |
| Q7Z6E9 | RBBP6 | 43.3 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| Q9UQ35 | SRRM2 | 42.5 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| Q16629 | SRSF7 | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9H307 | PNN | 64.6 | IV | Nuclear speckles | NMF result: nuclear body, SAFE result: spliceosomal complex II | 1 | 1 |
| Q9UBU9 | NXF1 | 50.3 | III | Nucleoplasm | NMF result: miscellaneous, SAFE result: nuclear pore | 1 | 1 |
| Q5T200 | ZC3H13 | 38.4 | II | Actin filaments;Nuclear membrane | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q14151 | SAFB2 | 45.8 | III | Nuclear bodies;Nucleoplasm;Vesicles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q96MU7 | YTHDC1 | 54.8 | IV | Nucleoplasm;Plasma membrane | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P27695 | APEX1 | 53.4 | III | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q8IWX8 | CHERP | 23.2 | II | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 | |
| Q07955 | SRSF1 | 41.6 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P08238 | HSP90AB1 | 46.0 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q15287 | RNPS1 | 58.0 | IV | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 1 | 1 |
| Q6PKG0 | LARP1 | 253.4 | VII | Cytosol;Endoplasmic reticulum;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| P52292 | KPNA2 | 53.6 | V | Cytosol;Nucleoplasm | NMF result: nucleoplasm, SAFE result: - | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9Y2W1 | THRAP3 | 37.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P07910 | HNRNPC | 47.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q13310 | PABPC4 | 147.7 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q5VTL8 | PRPF38B | 37.1 | II | NMF result: no prediction, SAFE result: no prediction | 1 | 1 | |
| Q14966 | ZNF638 | 47.8 | III | Nucleoplasm;Vesicles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9NYF8 | BCLAF1 | 37.5 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P38159 | RBMX | 44.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q8NEY8 | PPHLN1 | 35.3 | II | Golgi apparatus;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q13427 | PPIG | 53.4 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: spliceosomal complex II | 1 | 1 |
| Q9HCE1 | MOV10 | 221.0 | VII | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P11940 | PABPC1 | 124.3 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| P84103 | SRSF3 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |