MEPCE

UniProt Accession Q7L2J0 UniProt 🔗
Synonyms BCDIN3
UniProt protein names 7SK snRNA methylphosphate capping enzyme;
Bicoid-interacting protein 3 homolog
Peak binding time (min) 53.8
Cluster III
Cluster membership (corr) 0.997
Peak broadness (1 / std of log2 intensities) 1.38
Cluster expected from GO IV
Subcellular localization (Human Protein Atlas) Cell Junctions;Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: paraspeckles
RMSE (expected - observed) 0.39
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of MEPCE in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 2 5
P31943 HNRNPH1 40.8 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 3
O43395 PRPF3 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 4
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 4
Q9Y383 LUC7L2 29.7 II Nucleus NMF result: ER lumen, SAFE result: - 1 3
Q13595 TRA2A 42.2 II Nucleoli;Vesicles NMF result: no prediction, SAFE result: no prediction 1 3
Q9NQ29 LUC7L 43.6 II Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 1 3
Q86W50 METTL16 50.7 III Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 3
Q8WWY3 PRPF31 46.6 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 3
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 2
Q92841 DDX17 39.2 II Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 1 2
O75643 SNRNP200 42.7 II Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 2
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P17844 DDX5 40.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q9Y5A9 YTHDF2 111.0 VI Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 2
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P08238 HSP90AB1 46.0 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 2
P07910 HNRNPC 47.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q86V81 ALYREF 71.2 V NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 2
P16989 YBX3 137.7 VII Cytosol NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 2
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 2
P55795 HNRNPH2 36.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q96KR1 ZFR 46.6 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P67809 YBX1 148.5 VII Cytosol;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
Q9BUJ2 HNRNPUL1 42.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q1KMD3 HNRNPUL2 42.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q12905 ILF2 48.0 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 2
Q08211 DHX9 50.2 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 2
P38159 RBMX 44.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q00577 PURA 171.5 VII NMF result: no prediction, SAFE result: no prediction 1 2
Q13151 HNRNPA0 43.7 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q99729 HNRNPAB 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
O00425 IGF2BP3 149.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 2
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P61978 HNRNPK 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q9Y6M1 IGF2BP2 159.3 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
P52292 KPNA2 53.6 V Cytosol;Nucleoplasm NMF result: nucleoplasm, SAFE result: - 1 2
Q15366 PCBP2 48.9 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
Q9NZI8 IGF2BP1 143.9 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 2
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 2
P11021 HSPA5 48.9 III Cytosol NMF result: ER lumen, SAFE result: ER lumen 1 2
P78347 GTF2I 49.8 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 2
Q9BYJ9 YTHDF1 222.1 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 2
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 2
Q16629 SRSF7 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P43243 MATR3 47.9 III NMF result: nuclear body, SAFE result: paraspeckles 1 1
P42285 MTREX 73.4 V Nucleus NMF result: chromatin, SAFE result: - 1 1
O14602 EIF1AY 56.5 IV Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
O14979 HNRNPDL 43.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96E39 RBMXL1 45.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P04406 GAPDH 42.0 III Cytosol;Plasma membrane NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - 1 1
P07814 EPRS 29.5 II Cytosol NMF result: actin cytoskeleton, cytosol, SAFE result: cell junction, plasma membrane 1 1
P62314 SNRPD1 54.6 IV NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q8IWS0 PHF6 50.6 III Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: - 1 1
P21127 CDK11B 48.8 III Nuclear speckles NMF result: chromatin, SAFE result: - 1 1
Q6PKG0 LARP1 253.4 VII Cytosol;Endoplasmic reticulum;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P98179 RBM3 43.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15427 SF3B4 38.3 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q96SI9 STRBP 47.4 III NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9BZE4 GTPBP4 76.2 V Nuclear membrane;Nucleoli NMF result: nucleolus, SAFE result: no prediction 1 1
Q5SSJ5 HP1BP3 50.5 III Nuclear speckles NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P60842 EIF4A1 96.8 VI Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q9UN86 G3BP2 148.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q00610 CLTC 33.4 II Cytosol;Mitotic spindle;Vesicles NMF result: actin cytoskeleton, cytosol, SAFE result: no prediction 1 1
Q14331 FRG1 42.8 III NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9BQ67 GRWD1 42.3 II Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q9H2U1 DHX36 50.1 III Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P49761 CLK3 52.9 III Intermediate filaments;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
Q8ND56 LSM14A 138.4 VII Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9HAV4 XPO5 45.6 III Nucleoplasm NMF result: nucleolus, SAFE result: no prediction 1 1
P12236 SLC25A6 45.8 III Mitochondria NMF result: mitochondrial matrix, SAFE result: no prediction 1 1
Q9BYG3 NIFK 58.9 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P62633 CNBP 105.4 VI Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
O75616 ERAL1 48.7 IV Cytosol;Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P06733 ENO1 36.6 III Cytosol;Plasma membrane NMF result: miscellaneous, SAFE result: - 1 1
Q9NR30 DDX21 0.0 I Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9BX40 LSM14B 230.1 VII Nucleoli fibrillar center;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P17987 TCP1 45.1 III NMF result: miscellaneous, SAFE result: chaperonin-containing T-complex, prefoldin complex 1 1
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
O15372 EIF3H 64.3 IV Cytosol NMF result: centrosome, SAFE result: - 1 1
Q9Y3C1 NOP16 60.0 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q7Z2T5 TRMT1L 57.1 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P11142 HSPA8 45.1 III Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 1
Q14011 CIRBP 41.6 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q6P158 DHX57 78.3 VI Cytosol;Intermediate filaments;Microtubules;Nucleoli NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96QR8 PURB 143.9 VII Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9Y3Y2 CHTOP 75.6 V Nuclear speckles NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
P57723 PCBP4 47.4 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q13435 SF3B2 37.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P07437 TUBB 34.3 II Microtubules NMF result: no prediction, SAFE result: no prediction 1 1
P35659 DEK 45.5 II Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8NC51 SERBP1 213.4 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BZI7 UPF3B 64.9 V Cytosol;Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q07955 SRSF1 41.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P09874 PARP1 45.3 II Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9H0D6 XRN2 41.9 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14444 CAPRIN1 229.7 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q7Z739 YTHDF3 111.3 VI Cytosol;Nuclear membrane;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q13310 PABPC4 147.7 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P51991 HNRNPA3 43.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P14618 PKM 44.0 III Cytosol NMF result: miscellaneous, SAFE result: no prediction 1 1
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
O95232 LUC7L3 37.8 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P62995 TRA2B 42.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P11940 PABPC1 124.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q07065 CKAP4 40.2 II NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 1 1
O94906 PRPF6 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
P19338 NCL 27.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P35606 COPB2 47.6 III Cytosol NMF result: Golgi apparatus, SAFE result: Golgi apparatus 1 1
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BUQ8 DDX23 47.0 III Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
P05455 SSB 45.1 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q96EY7 PTCD3 77.4 V Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
Q15233 NONO 42.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O15371 EIF3D 208.1 VII Cytosol NMF result: miscellaneous, SAFE result: - 1 1
Q14498 RBM39 30.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P52272 HNRNPM 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q7L2E3 DHX30 56.5 IV Cytosol;Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
P68104 EEF1A1 42.8 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q8WUB8 PHF10 48.0 III Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9BQ39 DDX50 23.3 II Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P55081 MFAP1 43.9 II NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O15226 NKRF 47.5 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P37108 SRP14 45.6 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P52597 HNRNPF 42.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9BXS6 NUSAP1 52.2 III Nucleoli fibrillar center;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q12874 SF3A3 37.2 II Nucleoplasm NMF result: chromatin, SAFE result: splicing speckles, nucleolus 1 1
Q86XP3 DDX42 32.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8IX12 CCAR1 35.1 II Golgi apparatus;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P07900 HSP90AA1 48.1 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q9BY77 POLDIP3 74.6 V Cytoplasmic bodies;Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q96DH6 MSI2 93.6 V Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q7Z2W4 ZC3HAV1 211.8 VII Cytosol;Golgi apparatus NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 1 1