SF3A3

UniProt Accession Q12874 UniProt 🔗
Synonyms SAP61
UniProt protein names Splicing factor 3A subunit 3;
SF3a60;
Spliceosome-associated protein 61
Peak binding time (min) 37.2
Cluster II
Cluster membership (corr) 0.999
Peak broadness (1 / std of log2 intensities) 1.06
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: chromatin, SAFE result: splicing speckles, nucleolus
RMSE (expected - observed) 0.14
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of SF3A3 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q15459 SF3A1 43.6 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 9 8
Q15428 SF3A2 31.3 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 4
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 3
O14776 TCERG1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 2
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P09012 SNRPA 44.9 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q04637 EIF4G1 105.0 VI Cytosol NMF result: no prediction, SAFE result: no prediction 1 2
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q8WWY3 PRPF31 46.6 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 2
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 2
Q7L014 DDX46 38.1 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q9Y580 RBM7 36.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
O94906 PRPF6 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
O43395 PRPF3 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P43243 MATR3 47.9 III NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9BUQ8 DDX23 47.0 III Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
Q7KZF4 SND1 245.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13242 SRSF9 44.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UQ80 PA2G4 53.8 IV Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q8IZ69 TRMT2A 54.3 III Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P46013 MKI67 62.1 V Nuclear bodies;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P62314 SNRPD1 54.6 IV NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P31942 HNRNPH3 39.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q7L2J0 MEPCE 53.8 III Cell Junctions;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q15427 SF3B4 38.3 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O75940 SMNDC1 36.3 II Nuclear bodies;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q14966 ZNF638 47.8 III Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
O75400 PRPF40A 39.8 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P11142 HSPA8 45.1 III Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O75643 SNRNP200 42.7 II Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q9ULR0 ISY1 50.1 III Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1