SF3B1


UniProt Accession O75533 UniProt 🔗
Synonyms SAP155
UniProt protein names Splicing factor 3B subunit 1;
Pre-mRNA-splicing factor SF3b 155 kDa subunit;
Spliceosome-associated protein 155
Peak binding time (min) 40.9
Cluster II
Cluster membership (corr) 0.999
Peak broadness (1 / std of log2 intensities) 0.96
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Nuclear speckles
Subcellular localization (Human Cell Map) NMF result: no prediction, SAFE result: no prediction
RMSE (expected - observed) 0.16
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of SF3B1 in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q9Y3B4 SF3B6 36.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 5 7
Q7RTV0 PHF5A 37.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 4 5
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 3 5
Q13435 SF3B2 37.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 3 5
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 3 4
Q15427 SF3B4 38.3 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 3 4
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 3 3
Q15428 SF3A2 31.3 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 4
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
O14776 TCERG1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 2
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 2
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 2 2
Q86XP3 DDX42 32.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
Q9UIG0 BAZ1B 44.3 II Nuclear bodies NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 2 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
P09012 SNRPA 44.9 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 2
Q12874 SF3A3 37.2 II Nucleoplasm NMF result: chromatin, SAFE result: splicing speckles, nucleolus 1 2
Q15459 SF3A1 43.6 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 2
P62314 SNRPD1 54.6 IV NMF result: nuclear body, SAFE result: spliceosomal complex I 1 2
Q8WWY3 PRPF31 46.6 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 2
O75643 SNRNP200 42.7 II Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 2
Q9Y580 RBM7 36.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q15637 SF1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
O43395 PRPF3 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q96T37 RBM15 30.8 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
O43809 NUDT21 41.6 II Nuclear bodies NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P43243 MATR3 47.9 III NMF result: nuclear body, SAFE result: paraspeckles 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q14157 UBAP2L 212.4 VII Cytosol;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P18583 SON 43.3 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q14498 RBM39 30.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
P07814 EPRS 29.5 II Cytosol NMF result: actin cytoskeleton, cytosol, SAFE result: cell junction, plasma membrane 1 1
Q9UQ35 SRRM2 42.5 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P61978 HNRNPK 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P52272 HNRNPM 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96PK6 RBM14 42.9 II Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q07955 SRSF1 41.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P38919 EIF4A3 67.1 V Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P61326 MAGOH 70.2 V Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q7L2J0 MEPCE 53.8 III Cell Junctions;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P52292 KPNA2 53.6 V Cytosol;Nucleoplasm NMF result: nucleoplasm, SAFE result: - 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13243 SRSF5 41.7 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q12905 ILF2 48.0 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P09429 HMGB1 49.8 III Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q8TBF4 ZCRB1 36.7 II NMF result: no prediction, SAFE result: no prediction 1 1
O75940 SMNDC1 36.3 II Nuclear bodies;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q08945 SSRP1 0.0 I Cytosol;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P38159 RBMX 44.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O75400 PRPF40A 39.8 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q5BKZ1 ZNF326 44.1 II Golgi apparatus;Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: paraspeckles 1 1
O15260 SURF4 38.5 II NMF result: mitochondrial outer membrane, peroxisome, SAFE result: no prediction 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q13148 TARDBP 49.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P62995 TRA2B 42.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9UGY1 NOL12 73.1 V Nucleoli;Nucleus;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
Q9C0B0 UNK 88.4 VI Cytoplasmic bodies;Cytosol NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
Q9BQ67 GRWD1 42.3 II Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1