SERBP1

UniProt Accession Q8NC51 UniProt 🔗
Synonyms CGI-55, PAIRBP1
UniProt protein names SERPINE1 mRNA-binding protein 1;
PAI1 RNA-binding protein 1;
Plasminogen activator inhibitor 1 RNA-binding protein
Peak binding time (min) 213.4
Cluster VII
Cluster membership (corr) 0.983
Peak broadness (1 / std of log2 intensities) 1.09
Cluster expected from GO VII
Subcellular localization (Human Protein Atlas) Cytosol
Subcellular localization (Human Cell Map) NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule
RMSE (expected - observed) 0.22
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of SERBP1 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 3 3
Q14694 USP10 192.3 VII Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 3
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
O43395 PRPF3 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q15397 PUM3 58.6 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9NXF1 TEX10 94.1 V NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9UK59 DBR1 49.4 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9UNQ2 DIMT1 51.1 III Cytosol;Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
O75683 SURF6 56.6 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9H2U1 DHX36 50.1 III Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q13523 PRPF4B 45.4 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14562 DHX8 46.2 III Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q96QD9 FYTTD1 75.0 V Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q92615 LARP4B 233.7 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9Y2R4 DDX52 52.8 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9H6F5 CCDC86 98.8 VI Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9UQ80 PA2G4 53.8 IV Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
Q9BZI7 UPF3B 64.9 V Cytosol;Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q9P258 RCC2 44.9 III NMF result: no prediction, SAFE result: no prediction 1 1
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P27816 MAP4 62.7 V Cytosol;Microtubules;Plasma membrane NMF result: microtubule cytoskeleton, SAFE result: microtubule cytoskeleton 1 1
Q14241 ELOA 41.3 II Nuclear speckles NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P31943 HNRNPH1 40.8 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9BRJ6 C7orf50 51.1 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9BYG3 NIFK 58.9 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 1
Q7L2J0 MEPCE 53.8 III Cell Junctions;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q5JTH9 RRP12 53.2 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P21127 CDK11B 48.8 III Nuclear speckles NMF result: chromatin, SAFE result: - 1 1
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9H7E2 TDRD3 89.3 VI Cytosol;Golgi apparatus;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9NY93 DDX56 51.2 III NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9BU76 MMTAG2 41.6 II Cytosol;Nuclear speckles;Plasma membrane NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q6PK04 CCDC137 59.7 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9BTD8 RBM42 40.1 II Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9BZE4 GTPBP4 76.2 V Nuclear membrane;Nucleoli NMF result: nucleolus, SAFE result: no prediction 1 1
Q9H6S0 YTHDC2 171.0 VII Cytoplasmic bodies;Nuclear bodies;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9BXS6 NUSAP1 52.2 III Nucleoli fibrillar center;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9GZR7 DDX24 58.0 IV Cytosol;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O75940 SMNDC1 36.3 II Nuclear bodies;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9BTC0 DIDO1 29.8 II Cytosol;Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
Q1ED39 KNOP1 38.4 II Cytosol;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q00577 PURA 171.5 VII NMF result: no prediction, SAFE result: no prediction 1 1
Q9H7N4 SCAF1 31.3 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q13610 PWP1 44.9 II Golgi apparatus;Nucleoli NMF result: no prediction, SAFE result: no prediction 1 1
Q13823 GNL2 111.9 VI Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q8TED0 UTP15 46.7 III Endoplasmic reticulum;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9NZM5 NOP53 89.6 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q96GM8 TOE1 50.0 III Nuclear bodies;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P11940 PABPC1 124.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
O60231 DHX16 48.9 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q13206 DDX10 41.7 II Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8NHQ9 DDX55 78.7 V Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q52LJ0 FAM98B 62.5 IV Nucleoplasm;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13148 TARDBP 49.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1