DDX3X


UniProt Accession O00571 UniProt 🔗
Synonyms DBX, DDX3
UniProt protein names ATP-dependent RNA helicase DDX3X;
CAP-Rf;
DEAD box protein 3, X-chromosomal;
DEAD box, X isoform;
Helicase-like protein 2
Peak binding time (min) 146.2
Cluster VII
Cluster membership (corr) 0.998
Peak broadness (1 / std of log2 intensities) 1.24
Cluster expected from GO VI
Subcellular localization (Human Protein Atlas) Cytosol;Nucleus
Subcellular localization (Human Cell Map) NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction
RMSE (expected - observed) 0.09
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of DDX3X in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q9H7E2 TDRD3 89.3 VI Cytosol;Golgi apparatus;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 2
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 2 3
Q13283 G3BP1 220.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
O15372 EIF3H 64.3 IV Cytosol NMF result: centrosome, SAFE result: - 2 2
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
O15371 EIF3D 208.1 VII Cytosol NMF result: miscellaneous, SAFE result: - 2 2
P43243 MATR3 47.9 III NMF result: nuclear body, SAFE result: paraspeckles 1 3
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 2
Q9Y3I0 RTCB 54.9 IV Cytosol;Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: - 1 1
O14979 HNRNPDL 43.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9Y262 EIF3L 193.3 VII Nucleoli;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9UKV8 AGO2 103.6 VI Cell Junctions;Nucleoplasm NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q8TEQ6 GEMIN5 42.4 III Cytosol;Nuclear bodies NMF result: no prediction, SAFE result: no prediction 1 1
Q9NZI8 IGF2BP1 143.9 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P60842 EIF4A1 96.8 VI Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q9UN86 G3BP2 148.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
P78344 EIF4G2 200.0 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q13148 TARDBP 49.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q9NZB2 FAM120A 158.5 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9H2U1 DHX36 50.1 III Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q92615 LARP4B 233.7 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q92499 DDX1 74.7 V Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
P27695 APEX1 53.4 III Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9Y6M1 IGF2BP2 159.3 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q8ND56 LSM14A 138.4 VII Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9Y520 PRRC2C 147.3 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P31943 HNRNPH1 40.8 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P61326 MAGOH 70.2 V Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BX40 LSM14B 230.1 VII Nucleoli fibrillar center;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q92900 UPF1 158.9 VII Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96I24 FUBP3 51.8 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
O75821 EIF3G 105.9 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q14671 PUM1 104.1 VI Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q71RC2 LARP4 130.6 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96PZ0 PUS7 44.5 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q01804 OTUD4 99.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q6P158 DHX57 78.3 VI Cytosol;Intermediate filaments;Microtubules;Nucleoli NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UQ35 SRRM2 42.5 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O95985 TOP3B 72.2 V Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BYJ9 YTHDF1 222.1 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96CW1 AP2M1 45.0 III Plasma membrane NMF result: endosome, lysosome, SAFE result: endosome, lysosome 1 1
Q99700 ATXN2 116.5 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O00422 SAP18 63.4 IV Cytosol;Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P51114 FXR1 172.6 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13243 SRSF5 41.7 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q14444 CAPRIN1 229.7 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q7Z739 YTHDF3 111.3 VI Cytosol;Nuclear membrane;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q13310 PABPC4 147.7 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O75534 CSDE1 122.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q86V81 ALYREF 71.2 V NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q06787 FMR1 176.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P23588 EIF4B 213.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
P48634 PRRC2A 106.7 VI Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9BZZ5 API5 69.0 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9Y5A9 YTHDF2 111.0 VI Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q5VYS8 TUT7 75.9 V Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q7KZF4 SND1 245.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q14498 RBM39 30.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
Q13242 SRSF9 44.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P38919 EIF4A3 67.1 V Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q5JSZ5 PRRC2B 80.3 V Cytosol;Nuclear bodies NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q7L2J0 MEPCE 53.8 III Cell Junctions;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 1
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q17RY0 CPEB4 87.8 VI Golgi apparatus;Nucleoplasm;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q14694 USP10 192.3 VII Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9NX05 FAM120C 233.5 VII Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P12270 TPR 53.6 IV Nuclear membrane NMF result: no prediction, SAFE result: no prediction 1 1