CDK11B
| UniProt Accession | P21127 UniProt 🔗 |
|---|---|
| Synonyms | CDC2L1, CDK11, PITSLREA, PK58 |
| UniProt protein names | Cyclin-dependent kinase 11B;Cell division cycle 2-like protein kinase 1;Cell division protein kinase 11B;Galactosyltransferase-associated protein kinase p58/GTA;PITSLRE serine/threonine-protein kinase CDC2L1;p58 CLK-1 |
| Peak binding time (min) | 48.8 |
| Cluster | III |
| Cluster membership (corr) | 0.997 |
| Peak broadness (1 / std of log2 intensities) | 1.66 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Nuclear speckles |
| Subcellular localization (Human Cell Map) | NMF result: chromatin, SAFE result: - |
| RMSE (expected - observed) | 0.08 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of CDK11B in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P07900 | HSP90AA1 | 48.1 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P11142 | HSPA8 | 45.1 | III | Nucleoplasm;Vesicles | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
| O14617 | AP3D1 | 43.2 | III | Cytosol | NMF result: endosome, lysosome, SAFE result: endosome, lysosome | 1 | 1 |
| P26038 | MSN | 40.3 | II | Plasma membrane | NMF result: actin cytoskeleton, cytosol, SAFE result: cell junction, plasma membrane | 1 | 1 |
| Q96CW1 | AP2M1 | 45.0 | III | Plasma membrane | NMF result: endosome, lysosome, SAFE result: endosome, lysosome | 1 | 1 |
| Q8NC51 | SERBP1 | 213.4 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P31943 | HNRNPH1 | 40.8 | II | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P49756 | RBM25 | 34.8 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |
| Q15287 | RNPS1 | 58.0 | IV | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |