METTL16
| UniProt Accession | Q86W50 UniProt 🔗 |
|---|---|
| Synonyms | METT10D |
| UniProt protein names | RNA N6-adenosine-methyltransferase METTL16;Methyltransferase 10 domain-containing protein;Methyltransferase-like protein 16;N6-adenosine-methyltransferase METTL16;U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase |
| Peak binding time (min) | 50.7 |
| Cluster | III |
| Cluster membership (corr) | 0.993 |
| Peak broadness (1 / std of log2 intensities) | 1.15 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Cytosol;Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: no prediction, SAFE result: no prediction |
| RMSE (expected - observed) | 0.08 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of METTL16 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q7L2J0 | MEPCE | 53.8 | III | Cell Junctions;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 3 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q14320 | FAM50A | 42.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |