PCBP1


UniProt Accession Q15365 UniProt 🔗
Synonyms
UniProt protein names Poly(rC)-binding protein 1;
Alpha-CP1;
Heterogeneous nuclear ribonucleoprotein E1;
Nucleic acid-binding protein SUB2.3
Peak binding time (min) 48.6
Cluster III
Cluster membership (corr) 0.999
Peak broadness (1 / std of log2 intensities) 1.59
Cluster expected from GO V
Subcellular localization (Human Protein Atlas) Cytoplasmic bodies;Nuclear speckles
Subcellular localization (Human Cell Map) NMF result: no prediction, SAFE result: no prediction
RMSE (expected - observed) 0.56
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of PCBP1 in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q15366 PCBP2 48.9 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 4 4
P26599 PTBP1 46.5 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 4 3
P11940 PABPC1 124.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 3
Q13427 PPIG 53.4 III Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 3 2
Q13148 TARDBP 49.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 3
P43243 MATR3 47.9 III NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q8WVV9 HNRNPLL 43.8 II Cytosol;Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 2 2
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 2 2
P61978 HNRNPK 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q9Y6M1 IGF2BP2 159.3 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
P57723 PCBP4 47.4 III Cytosol NMF result: no prediction, SAFE result: no prediction 2 2
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 2 2
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q9BRZ2 TRIM56 74.3 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - 2 2
Q9UKM9 RALY 48.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q96PU8 QKI 47.1 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 1
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 2 1
P09012 SNRPA 44.9 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
P14618 PKM 44.0 III Cytosol NMF result: miscellaneous, SAFE result: no prediction 1 2
P08238 HSP90AB1 46.0 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 2
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
P07900 HSP90AA1 48.1 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 2
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 2
Q96AE4 FUBP1 36.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 2
O43251 RBFOX2 45.8 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 2
Q15637 SF1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UKV8 AGO2 103.6 VI Cell Junctions;Nucleoplasm NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9BWE0 REPIN1 51.4 III Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q15428 SF3A2 31.3 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q92804 TAF15 35.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O00154 ACOT7 38.3 II Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: - 1 1
P98179 RBM3 43.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9H0A0 NAT10 55.7 IV Midbody;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9NZI8 IGF2BP1 143.9 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q08211 DHX9 50.2 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q8N684 CPSF7 36.9 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9BQ67 GRWD1 42.3 II Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q9Y383 LUC7L2 29.7 II Nucleus NMF result: ER lumen, SAFE result: - 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
O00425 IGF2BP3 149.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9NZB2 FAM120A 158.5 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9UNQ2 DIMT1 51.1 III Cytosol;Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P63244 RACK1 43.3 III Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9H2U1 DHX36 50.1 III Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q96EP5 DAZAP1 37.4 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P62826 RAN 44.7 III NMF result: no prediction, SAFE result: no prediction 1 1
Q92499 DDX1 74.7 V Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
P46013 MKI67 62.1 V Nuclear bodies;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P52292 KPNA2 53.6 V Cytosol;Nucleoplasm NMF result: nucleoplasm, SAFE result: - 1 1
Q9BTD8 RBM42 40.1 II Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P20073 ANXA7 37.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O96028 NSD2 41.7 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9C0J8 WDR33 24.7 II Nucleoli fibrillar center;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q92900 UPF1 158.9 VII Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q96I24 FUBP3 51.8 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9Y3C1 NOP16 60.0 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q7Z2T5 TRMT1L 57.1 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9BVP2 GNL3 68.1 V Nuclear bodies;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9UKV3 ACIN1 60.5 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q07666 KHDRBS1 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q01804 OTUD4 99.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9H501 ESF1 45.4 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P17096 HMGA1 45.8 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q8IYB3 SRRM1 39.4 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9NQ29 LUC7L 43.6 II Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
O43395 PRPF3 48.3 III Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9NTZ6 RBM12 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O14776 TCERG1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q16658 FSCN1 42.1 II Cytosol;Plasma membrane NMF result: no prediction, SAFE result: no prediction 1 1
P07437 TUBB 34.3 II Microtubules NMF result: no prediction, SAFE result: no prediction 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q92879 CELF1 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9Y2R4 DDX52 52.8 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9BZI7 UPF3B 64.9 V Cytosol;Nucleoli;Nucleus NMF result: plasma membrane, SAFE result: - 1 1
Q96CW1 AP2M1 45.0 III Plasma membrane NMF result: endosome, lysosome, SAFE result: endosome, lysosome 1 1
O75340 PDCD6 37.8 II Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
P31942 HNRNPH3 39.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P24666 ACP1 45.5 III Cytosol;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P07910 HNRNPC 47.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q92576 PHF3 0.0 I Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P51991 HNRNPA3 43.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9GZR7 DDX24 58.0 IV Cytosol;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
O95758 PTBP3 55.2 IV Nucleus NMF result: nucleoplasm, SAFE result: - 1 1
Q8WWM7 ATXN2L 117.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P14866 HNRNPL 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P29401 TKT 46.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q13838 DDX39B 67.1 V Nuclear speckles NMF result: nuclear body, SAFE result: no prediction 1 1
O94906 PRPF6 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
P19338 NCL 27.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P17844 DDX5 40.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q7Z6E9 RBBP6 43.3 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P67809 YBX1 148.5 VII Cytosol;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
A0AV96 RBM47 58.8 IV Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q13247 SRSF6 45.9 II Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q9BZZ5 API5 69.0 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q15233 NONO 42.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14498 RBM39 30.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P52272 HNRNPM 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96PK6 RBM14 42.9 II Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 1 1
P68104 EEF1A1 42.8 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
O15042 U2SURP 33.1 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q7L2J0 MEPCE 53.8 III Cell Junctions;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P35637 FUS 37.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12905 ILF2 48.0 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9Y2W1 THRAP3 37.2 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q01085 TIAL1 46.1 II Nucleus;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q7Z417 NUFIP2 124.8 VI Cytosol;Nuclear bodies;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q13151 HNRNPA0 43.7 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9C0B0 UNK 88.4 VI Cytoplasmic bodies;Cytosol NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
P98175 RBM10 33.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1