EIF3L

UniProt Accession Q9Y262 UniProt 🔗
Synonyms EIF3EIP, EIF3S6IP, HSPC021, HSPC025, MSTP005
UniProt protein names Eukaryotic translation initiation factor 3 subunit L;
Eukaryotic translation initiation factor 3 subunit 6-interacting protein;
Eukaryotic translation initiation factor 3 subunit E-interacting protein
Peak binding time (min) 193.3
Cluster VII
Cluster membership (corr) 0.981
Peak broadness (1 / std of log2 intensities) 1.89
Cluster expected from GO VI
Subcellular localization (Human Protein Atlas) Nucleoli;Nucleus
Subcellular localization (Human Cell Map) NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction
RMSE (expected - observed) 0.28
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of EIF3L in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 6
O15371 EIF3D 208.1 VII Cytosol NMF result: miscellaneous, SAFE result: - 3 6
O15372 EIF3H 64.3 IV Cytosol NMF result: centrosome, SAFE result: - 2 6
O75821 EIF3G 105.9 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 4
B5ME19 EIF3CL 170.8 VII Cytosol NMF result: miscellaneous, SAFE result: - 2 2
P19338 NCL 27.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 2
Q8NDD1 C1orf131 57.7 IV Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q13283 G3BP1 220.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q5JSZ5 PRRC2B 80.3 V Cytosol;Nuclear bodies NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q6PKG0 LARP1 253.4 VII Cytosol;Endoplasmic reticulum;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9H0D6 XRN2 41.9 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
P23588 EIF4B 213.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
Q14980 NUMA1 47.8 III Nucleoplasm NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9H9G7 AGO3 91.6 VI Cytoplasmic bodies;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1