NSUN2
| UniProt Accession | Q08J23 UniProt 🔗 |
|---|---|
| Synonyms | SAKI, TRM4 |
| UniProt protein names | RNA cytosine C(5)-methyltransferase NSUN2;Myc-induced SUN domain-containing protein;NOL1/NOP2/Sun domain family member 2;Substrate of AIM1/Aurora kinase B;mRNA cytosine C(5)-methyltransferase;tRNA cytosine C(5)-methyltransferase;tRNA methyltransferase 4 homolog |
| Peak binding time (min) | 52.7 |
| Cluster | III |
| Cluster membership (corr) | 0.997 |
| Peak broadness (1 / std of log2 intensities) | 1.03 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Nucleus |
| Subcellular localization (Human Cell Map) | NMF result: miscellaneous, SAFE result: - |
| RMSE (expected - observed) | 0.07 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of NSUN2 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P06748 | NPM1 | 56.1 | IV | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 2 | 2 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P19338 | NCL | 27.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q13283 | G3BP1 | 220.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q96AE4 | FUBP1 | 36.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q96PZ0 | PUS7 | 44.5 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9Y6V7 | DDX49 | 46.5 | III | Mitochondria;Nucleoli | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P31943 | HNRNPH1 | 40.8 | II | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9HAV4 | XPO5 | 45.6 | III | Nucleoplasm | NMF result: nucleolus, SAFE result: no prediction | 1 | 1 |
| Q9NRX1 | PNO1 | 54.2 | IV | Nucleoli;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9BQ67 | GRWD1 | 42.3 | II | Nucleoli;Nucleus | NMF result: plasma membrane, SAFE result: - | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |