EXOSC9
| UniProt Accession | Q06265 UniProt 🔗 |
|---|---|
| Synonyms | PMSCL1 |
| UniProt protein names | Exosome complex component RRP45;Autoantigen PM/Scl 1;Exosome component 9;P75 polymyositis-scleroderma overlap syndrome-associated autoantigen;Polymyositis/scleroderma autoantigen 1;Polymyositis/scleroderma autoantigen 75 kDa |
| Peak binding time (min) | 54.5 |
| Cluster | IV |
| Cluster membership (corr) | 0.997 |
| Peak broadness (1 / std of log2 intensities) | 1.18 |
| Cluster expected from GO | IV |
| Subcellular localization (Human Protein Atlas) | Nucleoli;Nucleus |
| Subcellular localization (Human Cell Map) | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm |
| RMSE (expected - observed) | 0.16 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of EXOSC9 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q9NPD3 | EXOSC4 | 57.8 | IV | Cytosol;Intermediate filaments | NMF result: no prediction, SAFE result: no prediction | 4 | 7 |
| Q01780 | EXOSC10 | 58.1 | IV | Cytosol;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 3 | 4 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P46013 | MKI67 | 62.1 | V | Nuclear bodies;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P27695 | APEX1 | 53.4 | III | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P19338 | NCL | 27.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P67809 | YBX1 | 148.5 | VII | Cytosol;Vesicles | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q12986 | NFX1 | 77.5 | V | Cytosol;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q9H2Y7 | ZNF106 | 35.1 | II | Cytosol;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P29401 | TKT | 46.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9Y580 | RBM7 | 36.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |