MCM5
UniProt Accession | P33992 UniProt 🔗 |
---|---|
Synonyms | CDC46 |
UniProt protein names | DNA replication licensing factor MCM5;CDC46 homolog;P1-CDC46 |
Peak binding time (min) | 42.8 |
Cluster | III |
Cluster membership (corr) | 0.995 |
Peak broadness (1 / std of log2 intensities) | 1.16 |
Cluster expected from GO | IV |
Subcellular localization (Human Protein Atlas) | Nucleoplasm |
Subcellular localization (Human Cell Map) | NMF result: no prediction, SAFE result: no prediction |
RMSE (expected - observed) | 0.42 |
Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of MCM5 in mRNP (BioGRID)
Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
---|---|---|---|---|---|---|---|
P08238 | HSP90AB1 | 46.0 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 2 | 3 |
Q08945 | SSRP1 | 0.0 | I | Cytosol;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 2 | 2 |
O75533 | SF3B1 | 40.9 | II | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
P07900 | HSP90AA1 | 48.1 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
Q00839 | HNRNPU | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
Q12906 | ILF3 | 48.8 | III | Mitochondria;Nucleoli;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
Q99459 | CDC5L | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 2 | 2 |
Q12905 | ILF2 | 48.0 | III | Nucleoli;Nucleus | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
P19338 | NCL | 27.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
P17844 | DDX5 | 40.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
P67809 | YBX1 | 148.5 | VII | Cytosol;Vesicles | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
P43243 | MATR3 | 47.9 | III | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 | |
Q96E39 | RBMXL1 | 45.7 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
Q9BZZ5 | API5 | 69.0 | V | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
P23246 | SFPQ | 45.2 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
P07437 | TUBB | 34.3 | II | Microtubules | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
P04406 | GAPDH | 42.0 | III | Cytosol;Plasma membrane | NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - | 1 | 1 |
P11388 | TOP2A | 49.6 | III | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q13283 | G3BP1 | 220.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
P46013 | MKI67 | 62.1 | V | Nuclear bodies;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q15393 | SF3B3 | 45.7 | II | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
P46087 | NOP2 | 57.6 | IV | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
P68104 | EEF1A1 | 42.8 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
Q1KMD3 | HNRNPUL2 | 42.7 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
P11387 | TOP1 | 48.2 | III | Nucleoli fibrillar center;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
P06733 | ENO1 | 36.6 | III | Cytosol;Plasma membrane | NMF result: miscellaneous, SAFE result: - | 1 | 1 |
Q9NR30 | DDX21 | 0.0 | I | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
Q9H0A0 | NAT10 | 55.7 | IV | Midbody;Nucleoli | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q9Y2W1 | THRAP3 | 37.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
P07910 | HNRNPC | 47.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
P14618 | PKM | 44.0 | III | Cytosol | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
P51991 | HNRNPA3 | 43.2 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
Q08211 | DHX9 | 50.2 | III | Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
Q12874 | SF3A3 | 37.2 | II | Nucleoplasm | NMF result: chromatin, SAFE result: splicing speckles, nucleolus | 1 | 1 |
P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
O43143 | DHX15 | 35.8 | II | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
Q15459 | SF3A1 | 43.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
P38159 | RBMX | 44.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
P11142 | HSPA8 | 45.1 | III | Nucleoplasm;Vesicles | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
Q96PZ0 | PUS7 | 44.5 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q92841 | DDX17 | 39.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
Q15365 | PCBP1 | 48.6 | III | Cytoplasmic bodies;Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
Q96GQ7 | DDX27 | 62.3 | IV | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
O60506 | SYNCRIP | 71.4 | V | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles | 1 | 1 |
P22626 | HNRNPA2B1 | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
O75643 | SNRNP200 | 42.7 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: spliceosomal complex I | 1 | 1 |
Q9BQG0 | MYBBP1A | 54.4 | IV | Nucleoli;Vesicles | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
O43390 | HNRNPR | 48.0 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |