MCM5


UniProt Accession P33992 UniProt 🔗
Synonyms CDC46
UniProt protein names DNA replication licensing factor MCM5;
CDC46 homolog;
P1-CDC46
Peak binding time (min) 42.8
Cluster III
Cluster membership (corr) 0.995
Peak broadness (1 / std of log2 intensities) 1.16
Cluster expected from GO IV
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: no prediction, SAFE result: no prediction
RMSE (expected - observed) 0.42
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of MCM5 in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P08238 HSP90AB1 46.0 III Cytosol NMF result: no prediction, SAFE result: no prediction 2 3
Q08945 SSRP1 0.0 I Cytosol;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 2
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 2 2
P07900 HSP90AA1 48.1 III Cytosol NMF result: no prediction, SAFE result: no prediction 2 2
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q12905 ILF2 48.0 III Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 2 2
P19338 NCL 27.1 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P17844 DDX5 40.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P67809 YBX1 148.5 VII Cytosol;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P43243 MATR3 47.9 III NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q96E39 RBMXL1 45.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9BZZ5 API5 69.0 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P07437 TUBB 34.3 II Microtubules NMF result: no prediction, SAFE result: no prediction 1 1
P04406 GAPDH 42.0 III Cytosol;Plasma membrane NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - 1 1
P11388 TOP2A 49.6 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q13283 G3BP1 220.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P46013 MKI67 62.1 V Nuclear bodies;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P46087 NOP2 57.6 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P68104 EEF1A1 42.8 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q1KMD3 HNRNPUL2 42.7 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
P06733 ENO1 36.6 III Cytosol;Plasma membrane NMF result: miscellaneous, SAFE result: - 1 1
Q9NR30 DDX21 0.0 I Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9H0A0 NAT10 55.7 IV Midbody;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q9Y2W1 THRAP3 37.2 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P07910 HNRNPC 47.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P14618 PKM 44.0 III Cytosol NMF result: miscellaneous, SAFE result: no prediction 1 1
P51991 HNRNPA3 43.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q08211 DHX9 50.2 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12874 SF3A3 37.2 II Nucleoplasm NMF result: chromatin, SAFE result: splicing speckles, nucleolus 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q15459 SF3A1 43.6 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
P38159 RBMX 44.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P11142 HSPA8 45.1 III Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 1
Q96PZ0 PUS7 44.5 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q92841 DDX17 39.2 II Nuclear speckles NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q96GQ7 DDX27 62.3 IV Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O75643 SNRNP200 42.7 II Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q9BQG0 MYBBP1A 54.4 IV Nucleoli;Vesicles NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1