NOP53
| UniProt Accession | Q9NZM5 UniProt 🔗 |
|---|---|
| Synonyms | GLT, GLTSCR2, PICT1 |
| UniProt protein names | Ribosome biogenesis protein NOP53;Glioma tumor suppressor candidate region gene 2 protein;Protein interacting with carboxyl terminus 1;p60 |
| Peak binding time (min) | 89.6 |
| Cluster | V |
| Cluster membership (corr) | 0.962 |
| Peak broadness (1 / std of log2 intensities) | 1.49 |
| Cluster expected from GO | V |
| Subcellular localization (Human Protein Atlas) | Nucleoli |
| Subcellular localization (Human Cell Map) | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus |
| RMSE (expected - observed) | 0.15 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of NOP53 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q15397 | PUM3 | 58.6 | IV | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 2 | 2 |
| Q7L2E3 | DHX30 | 56.5 | IV | Cytosol;Mitochondria | NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix | 2 | 2 |
| Q9BZE4 | GTPBP4 | 76.2 | V | Nuclear membrane;Nucleoli | NMF result: nucleolus, SAFE result: no prediction | 2 | 2 |
| P06748 | NPM1 | 56.1 | IV | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| P42696 | RBM34 | 41.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P19338 | NCL | 27.1 | II | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P67809 | YBX1 | 148.5 | VII | Cytosol;Vesicles | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q96QD9 | FYTTD1 | 75.0 | V | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9H7B2 | RPF2 | 69.1 | V | Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: - | 1 | 1 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P46013 | MKI67 | 62.1 | V | Nuclear bodies;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q8NC51 | SERBP1 | 213.4 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q9H8H2 | DDX31 | 40.8 | II | Golgi apparatus;Nucleoli;Vesicles | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9NUL3 | STAU2 | 140.6 | VII | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P17480 | UBTF | 38.9 | II | Nucleoli fibrillar center | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P46087 | NOP2 | 57.6 | IV | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P62633 | CNBP | 105.4 | VI | Cytosol;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q5JTH9 | RRP12 | 53.2 | III | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q8IY81 | FTSJ3 | 69.4 | V | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q6PK04 | CCDC137 | 59.7 | V | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q8TDD1 | DDX54 | 67.3 | V | Golgi apparatus;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| O96028 | NSD2 | 41.7 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9H6S0 | YTHDC2 | 171.0 | VII | Cytoplasmic bodies;Nuclear bodies;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q8TBF4 | ZCRB1 | 36.7 | II | NMF result: no prediction, SAFE result: no prediction | 1 | 1 | |
| Q92900 | UPF1 | 158.9 | VII | Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q13823 | GNL2 | 111.9 | VI | Nucleoli | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9HCE1 | MOV10 | 221.0 | VII | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q8TDN6 | BRIX1 | 58.0 | IV | Nucleoli | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q96ME7 | ZNF512 | 45.2 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q96GQ7 | DDX27 | 62.3 | IV | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| O43159 | RRP8 | 43.2 | II | Cytosol;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9NW13 | RBM28 | 49.3 | III | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q8N567 | ZCCHC9 | 53.4 | IV | Intermediate filaments | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q13206 | DDX10 | 41.7 | II | Nucleoli | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q7Z2W4 | ZC3HAV1 | 211.8 | VII | Cytosol;Golgi apparatus | NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network | 1 | 1 |