HNRNPL
| UniProt Accession | P14866 UniProt 🔗 |
|---|---|
| Synonyms | HNRPL, P/OKcl.14 |
| UniProt protein names | Heterogeneous nuclear ribonucleoprotein L |
| Peak binding time (min) | 42.6 |
| Cluster | II |
| Cluster membership (corr) | 0.998 |
| Peak broadness (1 / std of log2 intensities) | 0.94 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: paraspeckles |
| RMSE (expected - observed) | 0.10 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of HNRNPL in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P22626 | HNRNPA2B1 | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 4 | 4 |
| P26599 | PTBP1 | 46.5 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 4 |
| P61978 | HNRNPK | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 3 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 5 |
| P31943 | HNRNPH1 | 40.8 | II | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 3 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 3 |
| Q9NR56 | MBNL1 | 49.5 | III | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 2 | 2 |
| P27695 | APEX1 | 53.4 | III | Nucleus | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| P51991 | HNRNPA3 | 43.2 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 2 | 2 |
| Q14103 | HNRNPD | 43.1 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 2 |
| Q8ND56 | LSM14A | 138.4 | VII | Cytoplasmic bodies;Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 2 | 2 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 2 | 2 |
| Q15366 | PCBP2 | 48.9 | III | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 2 | 1 |
| Q12906 | ILF3 | 48.8 | III | Mitochondria;Nucleoli;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 1 |
| P43243 | MATR3 | 47.9 | III | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 | |
| Q15637 | SF1 | 40.9 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q14157 | UBAP2L | 212.4 | VII | Cytosol;Nuclear speckles | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| O14979 | HNRNPDL | 43.3 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q99598 | TSNAX | 74.9 | V | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q9UKV8 | AGO2 | 103.6 | VI | Cell Junctions;Nucleoplasm | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| Q7KZ85 | SUPT6H | 0.0 | I | Cytosol;Nucleoplasm;Plasma membrane | NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q96PM9 | ZNF385A | 43.9 | II | Cytosol;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q8IY67 | RAVER1 | 48.3 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q8IWS0 | PHF6 | 50.6 | III | Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: - | 1 | 1 |
| O43251 | RBFOX2 | 45.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q6PKG0 | LARP1 | 253.4 | VII | Cytosol;Endoplasmic reticulum;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q92804 | TAF15 | 35.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9UPN6 | SCAF8 | 0.0 | I | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9GZT3 | SLIRP | 71.4 | V | Mitochondria | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9H0A0 | NAT10 | 55.7 | IV | Midbody;Nucleoli | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q5SSJ5 | HP1BP3 | 50.5 | III | Nuclear speckles | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q5VTL8 | PRPF38B | 37.1 | II | NMF result: no prediction, SAFE result: no prediction | 1 | 1 | |
| Q15361 | TTF1 | 26.0 | II | Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: no prediction | 1 | 1 |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |
| O14647 | CHD2 | 24.1 | II | Nucleus | NMF result: nucleoplasm, SAFE result: no prediction | 1 | 1 |
| Q9NVN8 | GNL3L | 135.5 | VI | Cytosol;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9UKA9 | PTBP2 | 44.3 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q8N5P1 | ZC3H8 | 51.6 | III | Nuclear bodies;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P84103 | SRSF3 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| O00425 | IGF2BP3 | 149.8 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q9NZB2 | FAM120A | 158.5 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q15149 | PLEC | 59.3 | V | Cytosol;Focal adhesion sites;Intermediate filaments | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q96EP5 | DAZAP1 | 37.4 | II | Cytosol;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q96QD9 | FYTTD1 | 75.0 | V | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9H7B2 | RPF2 | 69.1 | V | Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: - | 1 | 1 |
| Q99590 | SCAF11 | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P27816 | MAP4 | 62.7 | V | Cytosol;Microtubules;Plasma membrane | NMF result: microtubule cytoskeleton, SAFE result: microtubule cytoskeleton | 1 | 1 |
| P61326 | MAGOH | 70.2 | V | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O15234 | CASC3 | 88.1 | VI | Nuclear membrane | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9NY93 | DDX56 | 51.2 | III | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 | |
| P20073 | ANXA7 | 37.9 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O96028 | NSD2 | 41.7 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q14004 | CDK13 | 37.1 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q8IX01 | SUGP2 | 44.8 | II | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9BWF3 | RBM4 | 40.3 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9BVP2 | GNL3 | 68.1 | V | Nuclear bodies;Nucleoli | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q71RC2 | LARP4 | 130.6 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q8NEY8 | PPHLN1 | 35.3 | II | Golgi apparatus;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q92841 | DDX17 | 39.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q96ME7 | ZNF512 | 45.2 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q00839 | HNRNPU | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P17096 | HMGA1 | 45.8 | III | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9NQ29 | LUC7L | 43.6 | II | Mitochondria;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O43395 | PRPF3 | 48.3 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P11021 | HSPA5 | 48.9 | III | Cytosol | NMF result: ER lumen, SAFE result: ER lumen | 1 | 1 |
| O75152 | ZC3H11A | 63.2 | IV | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P23246 | SFPQ | 45.2 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P78347 | GTF2I | 49.8 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q92879 | CELF1 | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q5TC82 | RC3H1 | 62.0 | IV | Cytosol;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P78563 | ADARB1 | 48.2 | III | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9UQ35 | SRRM2 | 42.5 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q99700 | ATXN2 | 116.5 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| P11387 | TOP1 | 48.2 | III | Nucleoli fibrillar center;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9H0D6 | XRN2 | 41.9 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P07910 | HNRNPC | 47.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9UHX1 | PUF60 | 35.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| O75534 | CSDE1 | 122.4 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q86V81 | ALYREF | 71.2 | V | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 | |
| O95232 | LUC7L3 | 37.8 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: spliceosomal complex II | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P52756 | RBM5 | 33.5 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P11940 | PABPC1 | 124.3 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q15056 | EIF4H | 115.6 | VI | Cytosol;Nuclear bodies;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - | 1 | 1 |
| Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q05519 | SRSF11 | 52.0 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P78332 | RBM6 | 38.1 | II | Cytoplasmic bodies;Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9BZZ5 | API5 | 69.0 | V | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q14498 | RBM39 | 30.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| O43414 | ERI3 | 54.0 | III | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P52272 | HNRNPM | 46.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q7L2E3 | DHX30 | 56.5 | IV | Cytosol;Mitochondria | NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix | 1 | 1 |
| Q9BRJ6 | C7orf50 | 51.1 | III | Nucleoli;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P68104 | EEF1A1 | 42.8 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P38919 | EIF4A3 | 67.1 | V | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q96AE4 | FUBP1 | 36.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q12996 | CSTF3 | 9.6 | I | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9Y2W1 | THRAP3 | 37.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P52597 | HNRNPF | 42.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P61026 | RAB10 | 40.3 | II | NMF result: plasma membrane, SAFE result: no prediction | 1 | 1 | |
| Q9UKM9 | RALY | 48.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q14694 | USP10 | 192.3 | VII | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q14966 | ZNF638 | 47.8 | III | Nucleoplasm;Vesicles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q8IX12 | CCAR1 | 35.1 | II | Golgi apparatus;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O43143 | DHX15 | 35.8 | II | Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q00577 | PURA | 171.5 | VII | NMF result: no prediction, SAFE result: no prediction | 1 | 1 | |
| Q13151 | HNRNPA0 | 43.7 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q15365 | PCBP1 | 48.6 | III | Cytoplasmic bodies;Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q5VT52 | RPRD2 | 8.3 | I | Nucleoplasm;Vesicles | NMF result: nuclear body, SAFE result: spliceosomal complex II | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O60506 | SYNCRIP | 71.4 | V | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles | 1 | 1 |
| Q9NX05 | FAM120C | 233.5 | VII | Nuclear speckles | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q9C0B0 | UNK | 88.4 | VI | Cytoplasmic bodies;Cytosol | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| Q96DH6 | MSI2 | 93.6 | V | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q7Z2W4 | ZC3HAV1 | 211.8 | VII | Cytosol;Golgi apparatus | NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network | 1 | 1 |
| O43390 | HNRNPR | 48.0 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |