THRAP3
| UniProt Accession | Q9Y2W1 UniProt 🔗 |
|---|---|
| Synonyms | BCLAF2, TRAP150 |
| UniProt protein names | Thyroid hormone receptor-associated protein 3;BCLAF1 and THRAP3 family member 2;Thyroid hormone receptor-associated protein complex 150 kDa component |
| Peak binding time (min) | 37.2 |
| Cluster | II |
| Cluster membership (corr) | 0.999 |
| Peak broadness (1 / std of log2 intensities) | 0.85 |
| Cluster expected from GO | II |
| Subcellular localization (Human Protein Atlas) | Nuclear speckles |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus |
| RMSE (expected - observed) | 0.16 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of THRAP3 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q15287 | RNPS1 | 58.0 | IV | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 2 | 2 |
| Q9NYF8 | BCLAF1 | 37.5 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 2 | 2 |
| Q8TAD8 | SNIP1 | 40.9 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 3 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 1 | 2 |
| Q13595 | TRA2A | 42.2 | II | Nucleoli;Vesicles | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q9Y383 | LUC7L2 | 29.7 | II | Nucleus | NMF result: ER lumen, SAFE result: - | 1 | 2 |
| O94906 | PRPF6 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: spliceosomal complex I | 1 | 1 |
| Q05519 | SRSF11 | 52.0 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P17844 | DDX5 | 40.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q01844 | EWSR1 | 36.3 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O43395 | PRPF3 | 48.3 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q13435 | SF3B2 | 37.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9H307 | PNN | 64.6 | IV | Nuclear speckles | NMF result: nuclear body, SAFE result: spliceosomal complex II | 1 | 1 |
| Q15149 | PLEC | 59.3 | V | Cytosol;Focal adhesion sites;Intermediate filaments | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| P33992 | MCM5 | 42.8 | III | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9UNQ2 | DIMT1 | 51.1 | III | Cytosol;Nucleoli;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P43243 | MATR3 | 47.9 | III | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 | |
| Q96SB4 | SRPK1 | 52.0 | IV | Cytosol;Nucleus;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| Q9BZZ5 | API5 | 69.0 | V | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P49761 | CLK3 | 52.9 | III | Intermediate filaments;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P35659 | DEK | 45.5 | II | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9Y3B4 | SF3B6 | 36.0 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P23246 | SFPQ | 45.2 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O43290 | SART1 | 39.6 | II | Golgi apparatus;Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q5TC82 | RC3H1 | 62.0 | IV | Cytosol;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P27695 | APEX1 | 53.4 | III | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9NRR4 | DROSHA | 45.3 | III | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 | |
| P52272 | HNRNPM | 46.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O00422 | SAP18 | 63.4 | IV | Cytosol;Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q15393 | SF3B3 | 45.7 | II | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q96PK6 | RBM14 | 42.9 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P68104 | EEF1A1 | 42.8 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P38919 | EIF4A3 | 67.1 | V | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P61326 | MAGOH | 70.2 | V | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q92804 | TAF15 | 35.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P09874 | PARP1 | 45.3 | II | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9NR30 | DDX21 | 0.0 | I | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P09429 | HMGB1 | 49.8 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9NQ29 | LUC7L | 43.6 | II | Mitochondria;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O96028 | NSD2 | 41.7 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q13123 | IK | 51.9 | IV | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9UHX1 | PUF60 | 35.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q08211 | DHX9 | 50.2 | III | Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q86V81 | ALYREF | 71.2 | V | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 | |
| Q4G0J3 | LARP7 | 54.3 | IV | Cytosol;Nucleoplasm | NMF result: nucleolus, SAFE result: paraspeckles | 1 | 1 |
| Q15459 | SF3A1 | 43.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q08945 | SSRP1 | 0.0 | I | Cytosol;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q15365 | PCBP1 | 48.6 | III | Cytoplasmic bodies;Nuclear speckles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9UKV3 | ACIN1 | 60.5 | IV | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P14866 | HNRNPL | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q00839 | HNRNPU | 42.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q13838 | DDX39B | 67.1 | V | Nuclear speckles | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| Q9BQ67 | GRWD1 | 42.3 | II | Nucleoli;Nucleus | NMF result: plasma membrane, SAFE result: - | 1 | 1 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |