AP2M1

UniProt Accession Q96CW1 UniProt 🔗
Synonyms CLAPM1, KIAA0109
UniProt protein names AP-2 complex subunit mu;
AP-2 mu chain;
Adaptin-mu2;
Adaptor protein complex AP-2 subunit mu;
Adaptor-related protein complex 2 subunit mu;
Clathrin assembly protein complex 2 mu medium chain;
Clathrin coat assembly protein AP50;
Clathrin coat-associated protein AP50;
HA2 50 kDa subunit;
Plasma membrane adaptor AP-2 50 kDa protein
Peak binding time (min) 45.0
Cluster III
Cluster membership (corr) 0.998
Peak broadness (1 / std of log2 intensities) 1.63
Cluster expected from GO II
Subcellular localization (Human Protein Atlas) Plasma membrane
Subcellular localization (Human Cell Map) NMF result: endosome, lysosome, SAFE result: endosome, lysosome
RMSE (expected - observed) 0.18
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of AP2M1 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P11142 HSPA8 45.1 III Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 2
Q8NEY8 PPHLN1 35.3 II Golgi apparatus;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 2
Q00610 CLTC 33.4 II Cytosol;Mitotic spindle;Vesicles NMF result: actin cytoskeleton, cytosol, SAFE result: no prediction 1 2
P07437 TUBB 34.3 II Microtubules NMF result: no prediction, SAFE result: no prediction 1 2
Q9UNQ2 DIMT1 51.1 III Cytosol;Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P04406 GAPDH 42.0 III Cytosol;Plasma membrane NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - 1 1
Q8N5F7 NKAP 47.0 III Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q9UK61 FAM208A 0.0 I Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P27816 MAP4 62.7 V Cytosol;Microtubules;Plasma membrane NMF result: microtubule cytoskeleton, SAFE result: microtubule cytoskeleton 1 1
P51114 FXR1 172.6 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P68104 EEF1A1 42.8 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
P12236 SLC25A6 45.8 III Mitochondria NMF result: mitochondrial matrix, SAFE result: no prediction 1 1
Q5JTH9 RRP12 53.2 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P21127 CDK11B 48.8 III Nuclear speckles NMF result: chromatin, SAFE result: - 1 1
P55081 MFAP1 43.9 II NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9BU76 MMTAG2 41.6 II Cytosol;Nuclear speckles;Plasma membrane NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9H0S4 DDX47 49.7 III Nucleoli NMF result: miscellaneous, SAFE result: - 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
Q1ED39 KNOP1 38.4 II Cytosol;Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q8WWM7 ATXN2L 117.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15365 PCBP1 48.6 III Cytoplasmic bodies;Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P22626 HNRNPA2B1 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13838 DDX39B 67.1 V Nuclear speckles NMF result: nuclear body, SAFE result: no prediction 1 1