SPEN


UniProt Accession Q96T58 UniProt 🔗
Synonyms KIAA0929, MINT, SHARP
UniProt protein names Msx2-interacting protein;
SMART/HDAC1-associated repressor protein;
SPEN homolog
Peak binding time (min) 33.1
Cluster II
Cluster membership (corr) 0.998
Peak broadness (1 / std of log2 intensities) 0.96
Cluster expected from GO IV
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: chromatin, nucleoplasm
RMSE (expected - observed) 0.49
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of SPEN in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P46013 MKI67 62.1 V Nuclear bodies;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O00267 SUPT5H 0.0 I Nucleoplasm NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
P52298 NCBP2 45.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P17096 HMGA1 45.8 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9NYF8 BCLAF1 37.5 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1