SPEN
UniProt Accession | Q96T58 UniProt 🔗 |
---|---|
Synonyms | KIAA0929, MINT, SHARP |
UniProt protein names | Msx2-interacting protein;SMART/HDAC1-associated repressor protein;SPEN homolog |
Peak binding time (min) | 33.1 |
Cluster | II |
Cluster membership (corr) | 0.998 |
Peak broadness (1 / std of log2 intensities) | 0.96 |
Cluster expected from GO | IV |
Subcellular localization (Human Protein Atlas) | Nucleoplasm |
Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm |
RMSE (expected - observed) | 0.49 |
Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of SPEN in mRNP (BioGRID)
Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
---|---|---|---|---|---|---|---|
P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
P46013 | MKI67 | 62.1 | V | Nuclear bodies;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
O00267 | SUPT5H | 0.0 | I | Nucleoplasm | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
P52298 | NCBP2 | 45.8 | III | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
P17096 | HMGA1 | 45.8 | III | Nucleoli;Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
Q9NYF8 | BCLAF1 | 37.5 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |