G3BP1


UniProt Accession Q13283 UniProt 🔗
Synonyms G3BP
UniProt protein names Ras GTPase-activating protein-binding protein 1;
ATP-dependent DNA helicase VIII;
GAP SH3 domain-binding protein 1
Peak binding time (min) 220.8
Cluster VII
Cluster membership (corr) 0.994
Peak broadness (1 / std of log2 intensities) 1.20
Cluster expected from GO VII
Subcellular localization (Human Protein Atlas) Cytosol
Subcellular localization (Human Cell Map) NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule
RMSE (expected - observed) 0.14
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of G3BP1 in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
Q14694 USP10 192.3 VII Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 6 12
Q14444 CAPRIN1 229.7 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 4 5
P11940 PABPC1 124.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 4
Q14157 UBAP2L 212.4 VII Cytosol;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 3
Q13310 PABPC4 147.7 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 3
Q7KZF4 SND1 245.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 3 2
Q9UN86 G3BP2 148.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 4
Q7Z417 NUFIP2 124.8 VI Cytosol;Nuclear bodies;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 4
P51116 FXR2 171.1 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 3
Q8WWM7 ATXN2L 117.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 3
Q9UKV8 AGO2 103.6 VI Cell Junctions;Nucleoplasm NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 2 3
Q9BYJ9 YTHDF1 222.1 VII NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 3
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 2 2
Q9Y520 PRRC2C 147.3 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
P29558 RBMS1 107.1 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q99700 ATXN2 116.5 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q9Y6M1 IGF2BP2 159.3 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
Q96I24 FUBP3 51.8 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 2 2
Q14671 PUM1 104.1 VI Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q92900 UPF1 158.9 VII Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q01804 OTUD4 99.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q92879 CELF1 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 2 2
Q5T6F2 UBAP2 209.7 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q7Z739 YTHDF3 111.3 VI Cytosol;Nuclear membrane;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
Q71RC2 LARP4 130.6 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q7Z2W4 ZC3HAV1 211.8 VII Cytosol;Golgi apparatus NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 2 2
P48634 PRRC2A 106.7 VI Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
P67809 YBX1 148.5 VII Cytosol;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
Q8ND56 LSM14A 138.4 VII Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q9Y5A9 YTHDF2 111.0 VI Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
P51114 FXR1 172.6 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 2
Q9NZI8 IGF2BP1 143.9 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
O75534 CSDE1 122.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q06787 FMR1 176.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 2 2
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 1
Q04637 EIF4G1 105.0 VI Cytosol NMF result: no prediction, SAFE result: no prediction 1 2
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
Q13148 TARDBP 49.3 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
P46013 MKI67 62.1 V Nuclear bodies;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 2
Q08170 SRSF4 44.0 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9Y3I0 RTCB 54.9 IV Cytosol;Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: - 1 1
Q9Y262 EIF3L 193.3 VII Nucleoli;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P04406 GAPDH 42.0 III Cytosol;Plasma membrane NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - 1 1
P30876 POLR2B 0.0 I Nucleoplasm NMF result: miscellaneous, SAFE result: chromatin, nucleoplasm 1 1
Q05048 CSTF1 22.4 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q8IXT5 RBM12B 48.7 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q6PKG0 LARP1 253.4 VII Cytosol;Endoplasmic reticulum;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P60842 EIF4A1 96.8 VI Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
O15143 ARPC1B 49.8 III Cytosol;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
Q6Y7W6 GIGYF2 61.8 IV Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O15347 HMGB3 46.3 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q8N684 CPSF7 36.9 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9BYK8 HELZ2 68.9 V NMF result: no prediction, SAFE result: no prediction 1 1
P78344 EIF4G2 200.0 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
O00425 IGF2BP3 149.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9NZB2 FAM120A 158.5 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q96EP5 DAZAP1 37.4 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q92615 LARP4B 233.7 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q92499 DDX1 74.7 V Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P27695 APEX1 53.4 III Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P07195 LDHB 56.6 IV Cytosol NMF result: miscellaneous, SAFE result: no prediction 1 1
Q9P258 RCC2 44.9 III NMF result: no prediction, SAFE result: no prediction 1 1
P27816 MAP4 62.7 V Cytosol;Microtubules;Plasma membrane NMF result: microtubule cytoskeleton, SAFE result: microtubule cytoskeleton 1 1
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P52292 KPNA2 53.6 V Cytosol;Nucleoplasm NMF result: nucleoplasm, SAFE result: - 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9NR30 DDX21 0.0 I Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P20073 ANXA7 37.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9BX40 LSM14B 230.1 VII Nucleoli fibrillar center;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P17987 TCP1 45.1 III NMF result: miscellaneous, SAFE result: chaperonin-containing T-complex, prefoldin complex 1 1
Q8IX01 SUGP2 44.8 II Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q5T8P6 RBM26 53.9 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O75821 EIF3G 105.9 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O15372 EIF3H 64.3 IV Cytosol NMF result: centrosome, SAFE result: - 1 1
P62820 RAB1A 45.1 III Cytosol;Endoplasmic reticulum NMF result: mitochondrial outer membrane, peroxisome, SAFE result: no prediction 1 1
Q9NW64 RBM22 48.0 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P17096 HMGA1 45.8 III Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q96QR8 PURB 143.9 VII Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q9NQ29 LUC7L 43.6 II Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q16658 FSCN1 42.1 II Cytosol;Plasma membrane NMF result: no prediction, SAFE result: no prediction 1 1
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
O95985 TOP3B 72.2 V Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9BXP5 SRRT 44.7 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q16630 CPSF6 33.9 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P26599 PTBP1 46.5 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P51991 HNRNPA3 43.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P16989 YBX3 137.7 VII Cytosol NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P23588 EIF4B 213.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
O95758 PTBP3 55.2 IV Nucleus NMF result: nucleoplasm, SAFE result: - 1 1
Q9HCE1 MOV10 221.0 VII Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P55795 HNRNPH2 36.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q15056 EIF4H 115.6 VI Cytosol;Nuclear bodies;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q9H9G7 AGO3 91.6 VI Cytoplasmic bodies;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9NUQ6 SPATS2L 60.2 V Cytosol;Nucleoli NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - 1 1
P33992 MCM5 42.8 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q14151 SAFB2 45.8 III Nuclear bodies;Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O15371 EIF3D 208.1 VII Cytosol NMF result: miscellaneous, SAFE result: - 1 1
Q6PJT7 ZC3H14 65.7 IV Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q9BUJ2 HNRNPUL1 42.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UQ80 PA2G4 53.8 IV Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q7L2E3 DHX30 56.5 IV Cytosol;Mitochondria NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix 1 1
Q9NUL3 STAU2 140.6 VII Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q9UGR2 ZC3H7B 80.7 VI NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9BQ39 DDX50 23.3 II Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
Q5JSZ5 PRRC2B 80.3 V Cytosol;Nuclear bodies NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9H7E2 TDRD3 89.3 VI Cytosol;Golgi apparatus;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P55081 MFAP1 43.9 II NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9BRZ2 TRIM56 74.3 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - 1 1
Q92522 H1FX 41.6 II Nucleoli;Nucleus NMF result: nucleolus, SAFE result: no prediction 1 1
Q17RY0 CPEB4 87.8 VI Golgi apparatus;Nucleoplasm;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q13123 IK 51.9 IV Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q08J23 NSUN2 52.7 III Nucleus NMF result: miscellaneous, SAFE result: - 1 1
Q01085 TIAL1 46.1 II Nucleus;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
Q9UHD1 CHORDC1 39.0 III Cytosol NMF result: miscellaneous, SAFE result: - 1 1
Q96QC0 PPP1R10 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q9H0S4 DDX47 49.7 III Nucleoli NMF result: miscellaneous, SAFE result: - 1 1
Q14966 ZNF638 47.8 III Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P07900 HSP90AA1 48.1 III Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q00577 PURA 171.5 VII NMF result: no prediction, SAFE result: no prediction 1 1
Q13823 GNL2 111.9 VI Nucleoli NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q99729 HNRNPAB 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9C0B0 UNK 88.4 VI Cytoplasmic bodies;Cytosol NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
P55265 ADAR 48.0 III Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q96DH6 MSI2 93.6 V Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
Q8TB72 PUM2 91.4 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1