SCAF11
| UniProt Accession | Q99590 UniProt 🔗 |
|---|---|
| Synonyms | CASP11, SFRS2IP, SIP1, SRSF2IP |
| UniProt protein names | Protein SCAF11;CTD-associated SR protein 11;Renal carcinoma antigen NY-REN-40;SC35-interacting protein 1;SR-related and CTD-associated factor 11;SRSF2-interacting protein;Serine/arginine-rich splicing factor 2-interacting protein;Splicing factor, arginine/serine-rich 2-interacting protein;Splicing regulatory protein 129 |
| Peak binding time (min) | 0.0 |
| Cluster | I |
| Cluster membership (corr) | 0.992 |
| Peak broadness (1 / std of log2 intensities) | 0.79 |
| Cluster expected from GO | II |
| Subcellular localization (Human Protein Atlas) | Nuclear bodies;Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm |
| RMSE (expected - observed) | 0.39 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of SCAF11 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 4 | 3 |
| Q9Y383 | LUC7L2 | 29.7 | II | Nucleus | NMF result: ER lumen, SAFE result: - | 1 | 2 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P46013 | MKI67 | 62.1 | V | Nuclear bodies;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9P2E3 | ZNFX1 | 233.0 | VII | Mitochondria | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P14866 | HNRNPL | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O00267 | SUPT5H | 0.0 | I | Nucleoplasm | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q07955 | SRSF1 | 41.6 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P12236 | SLC25A6 | 45.8 | III | Mitochondria | NMF result: mitochondrial matrix, SAFE result: no prediction | 1 | 1 |
| Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P84103 | SRSF3 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| Q92804 | TAF15 | 35.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |