LDHA
| UniProt Accession | P00338 UniProt 🔗 |
|---|---|
| Synonyms | PIG19 |
| UniProt protein names | L-lactate dehydrogenase A chain;Cell proliferation-inducing gene 19 protein;LDH muscle subunit;Renal carcinoma antigen NY-REN-59 |
| Peak binding time (min) | 44.4 |
| Cluster | III |
| Cluster membership (corr) | 0.956 |
| Peak broadness (1 / std of log2 intensities) | 1.80 |
| Cluster expected from GO | II |
| Subcellular localization (Human Protein Atlas) | Cytosol;Vesicles |
| Subcellular localization (Human Cell Map) | NMF result: miscellaneous, SAFE result: no prediction |
| RMSE (expected - observed) | 0.14 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of LDHA in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| P07195 | LDHB | 56.6 | IV | Cytosol | NMF result: miscellaneous, SAFE result: no prediction | 3 | 8 |
| P07900 | HSP90AA1 | 48.1 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P06733 | ENO1 | 36.6 | III | Cytosol;Plasma membrane | NMF result: miscellaneous, SAFE result: - | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P46013 | MKI67 | 62.1 | V | Nuclear bodies;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q12986 | NFX1 | 77.5 | V | Cytosol;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| P14618 | PKM | 44.0 | III | Cytosol | NMF result: miscellaneous, SAFE result: no prediction | 1 | 1 |
| P27694 | RPA1 | 45.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9C0B0 | UNK | 88.4 | VI | Cytoplasmic bodies;Cytosol | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched | 1 | 1 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P08238 | HSP90AB1 | 46.0 | III | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P29401 | TKT | 46.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P62820 | RAB1A | 45.1 | III | Cytosol;Endoplasmic reticulum | NMF result: mitochondrial outer membrane, peroxisome, SAFE result: no prediction | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q13148 | TARDBP | 49.3 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |