FIP1L1
| UniProt Accession | Q6UN15 UniProt 🔗 |
|---|---|
| Synonyms | FIP1, RHE |
| UniProt protein names | Pre-mRNA 3'-end-processing factor FIP1;FIP1-like 1 protein;Factor interacting with PAP;Rearranged in hypereosinophilia |
| Peak binding time (min) | 19.3 |
| Cluster | I |
| Cluster membership (corr) | 0.992 |
| Peak broadness (1 / std of log2 intensities) | 0.89 |
| Cluster expected from GO | II |
| Subcellular localization (Human Protein Atlas) | Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus |
| RMSE (expected - observed) | 0.05 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of FIP1L1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| O95639 | CPSF4 | 36.9 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 4 | 6 |
| Q9C0J8 | WDR33 | 24.7 | II | Nucleoli fibrillar center;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 3 | 3 |
| Q12996 | CSTF3 | 9.6 | I | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 2 |
| Q9H0L4 | CSTF2T | 14.0 | I | Nucleoplasm | NMF result: actin cytoskeleton, cytosol, SAFE result: no prediction | 2 | 2 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 2 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| O95793 | STAU1 | 111.0 | VI | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P46013 | MKI67 | 62.1 | V | Nuclear bodies;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| P09429 | HMGB1 | 49.8 | III | Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9UQ35 | SRRM2 | 42.5 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q05048 | CSTF1 | 22.4 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q13573 | SNW1 | 51.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q14839 | CHD4 | 61.8 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q5TC82 | RC3H1 | 62.0 | IV | Cytosol;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |
| P33240 | CSTF2 | 23.7 | II | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| Q8TAD8 | SNIP1 | 40.9 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q12873 | CHD3 | 52.4 | IV | Microtubule organizing center;Nucleoli;Nucleus | NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm | 1 | 1 |