SRSF8


UniProt Accession Q9BRL6 UniProt 🔗
Synonyms SFRS2B, SRP46
UniProt protein names Serine/arginine-rich splicing factor 8;
Pre-mRNA-splicing factor SRP46;
Splicing factor, arginine/serine-rich 2B
Peak binding time (min) 42.6
Cluster II
Cluster membership (corr) 0.994
Peak broadness (1 / std of log2 intensities) 1.14
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Cytosol;Nucleus
Subcellular localization (Human Cell Map) NMF result: no prediction, SAFE result: no prediction
RMSE (expected - observed) 0.15
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of SRSF8 in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P49761 CLK3 52.9 III Intermediate filaments;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
Q96SB4 SRPK1 52.0 IV Cytosol;Nucleus;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 2 1
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q13595 TRA2A 42.2 II Nucleoli;Vesicles NMF result: no prediction, SAFE result: no prediction 1 2
Q9NQ29 LUC7L 43.6 II Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 1 2
Q9Y383 LUC7L2 29.7 II Nucleus NMF result: ER lumen, SAFE result: - 1 2
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
P46013 MKI67 62.1 V Nuclear bodies;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: chromatin, nucleoplasm 1 1
P62995 TRA2B 42.0 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P61326 MAGOH 70.2 V Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1