ZFC3H1
| UniProt Accession | O60293 UniProt 🔗 |
|---|---|
| Synonyms | CCDC131, KIAA0546, PSRC2 |
| UniProt protein names | Zinc finger C3H1 domain-containing protein;Coiled-coil domain-containing protein 131;Proline/serine-rich coiled-coil protein 2 |
| Peak binding time (min) | 51.3 |
| Cluster | III |
| Cluster membership (corr) | 0.991 |
| Peak broadness (1 / std of log2 intensities) | 1.94 |
| Cluster expected from GO | III |
| Subcellular localization (Human Protein Atlas) | Intermediate filaments;Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus |
| RMSE (expected - observed) | 0.21 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of ZFC3H1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 2 |
| Q8IUH3 | RBM45 | 45.8 | III | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P42285 | MTREX | 73.4 | V | Nucleus | NMF result: chromatin, SAFE result: - | 1 | 1 |
| Q9P2N5 | RBM27 | 49.2 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9H000 | MKRN2 | 65.9 | V | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q96EY7 | PTCD3 | 77.4 | V | Mitochondria | NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix | 1 | 1 |
| P61978 | HNRNPK | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q96PV6 | LENG8 | 50.0 | III | Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q7L2E3 | DHX30 | 56.5 | IV | Cytosol;Mitochondria | NMF result: mitochondrial matrix, SAFE result: mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix | 1 | 1 |
| Q9BXP5 | SRRT | 44.7 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: no prediction | 1 | 1 |
| P52298 | NCBP2 | 45.8 | III | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q6PKG0 | LARP1 | 253.4 | VII | Cytosol;Endoplasmic reticulum;Nucleus | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q13310 | PABPC4 | 147.7 | VII | Cytosol | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q92900 | UPF1 | 158.9 | VII | Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule | 1 | 1 |
| Q9UKM9 | RALY | 48.9 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q8NEY8 | PPHLN1 | 35.3 | II | Golgi apparatus;Nucleoplasm | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q01780 | EXOSC10 | 58.1 | IV | Cytosol;Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q9HCE1 | MOV10 | 221.0 | VII | Cytosol | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P55265 | ADAR | 48.0 | III | Nucleoli;Nucleus | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |