YTHDC1
| UniProt Accession | Q96MU7 UniProt 🔗 |
|---|---|
| Synonyms | KIAA1966, YT521 |
| UniProt protein names | YTH domain-containing protein 1;Splicing factor YT521 |
| Peak binding time (min) | 54.8 |
| Cluster | IV |
| Cluster membership (corr) | 0.989 |
| Peak broadness (1 / std of log2 intensities) | 1.14 |
| Cluster expected from GO | IV |
| Subcellular localization (Human Protein Atlas) | Nucleoplasm;Plasma membrane |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus |
| RMSE (expected - observed) | 0.07 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of YTHDC1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q96SB4 | SRPK1 | 52.0 | IV | Cytosol;Nucleus;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 3 | 1 |
| Q13595 | TRA2A | 42.2 | II | Nucleoli;Vesicles | NMF result: no prediction, SAFE result: no prediction | 2 | 3 |
| Q07666 | KHDRBS1 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 1 |
| Q8TAD8 | SNIP1 | 40.9 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 3 |
| P61978 | HNRNPK | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 3 |
| P62995 | TRA2B | 42.0 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| P38159 | RBMX | 44.4 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 2 |
| P08621 | SNRNP70 | 32.2 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 2 |
| Q12905 | ILF2 | 48.0 | III | Nucleoli;Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P49761 | CLK3 | 52.9 | III | Intermediate filaments;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P09651 | HNRNPA1 | 43.1 | II | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| P38919 | EIF4A3 | 67.1 | V | Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q15287 | RNPS1 | 58.0 | IV | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P61326 | MAGOH | 70.2 | V | Nucleus | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q5TC82 | RC3H1 | 62.0 | IV | Cytosol;Plasma membrane | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction | 1 | 1 |