PRPF40A


UniProt Accession O75400 UniProt 🔗
Synonyms FBP11, FLAF1, FNBP3, HIP10, HSPC225, HYPA
UniProt protein names Pre-mRNA-processing factor 40 homolog A;
Fas ligand-associated factor 1;
Formin-binding protein 11;
Formin-binding protein 3;
Huntingtin yeast partner A;
Huntingtin-interacting protein 10;
Huntingtin-interacting protein A;
Renal carcinoma antigen NY-REN-6
Peak binding time (min) 39.8
Cluster II
Cluster membership (corr) 0.999
Peak broadness (1 / std of log2 intensities) 1.34
Cluster expected from GO II
Subcellular localization (Human Protein Atlas) Nuclear speckles
Subcellular localization (Human Cell Map) NMF result: nuclear body, SAFE result: chromatin, nucleoplasm
RMSE (expected - observed) 0.06
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of PRPF40A in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P08621 SNRNP70 32.2 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 3 3
Q8N5F7 NKAP 47.0 III Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex II 3 3
Q15459 SF3A1 43.6 II Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 3 2
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 3 2
Q15287 RNPS1 58.0 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 4
Q7L014 DDX46 38.1 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 3
Q13435 SF3B2 37.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q9UQ35 SRRM2 42.5 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q15428 SF3A2 31.3 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 2
Q53F19 NCBP3 77.1 V Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 2
Q9UKV3 ACIN1 60.5 IV Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q9NQ29 LUC7L 43.6 II Mitochondria;Nucleus NMF result: no prediction, SAFE result: no prediction 1 2
Q15637 SF1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q9H307 PNN 64.6 IV Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 2
Q9Y3X0 CCDC9 81.3 V Cytosol NMF result: no prediction, SAFE result: no prediction 1 2
Q9BUJ2 HNRNPUL1 42.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 2
Q14498 RBM39 30.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 2
P17844 DDX5 40.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q01844 EWSR1 36.3 II Nucleoli;Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q8NDD1 C1orf131 57.7 IV Cytosol;Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
P67809 YBX1 148.5 VII Cytosol;Vesicles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
O14776 TCERG1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P27694 RPA1 45.5 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P23246 SFPQ 45.2 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P49756 RBM25 34.8 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q14562 DHX8 46.2 III Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
Q15233 NONO 42.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P18583 SON 43.3 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P04406 GAPDH 42.0 III Cytosol;Plasma membrane NMF result: mitochondrial outer membrane, peroxisome, SAFE result: - 1 1
Q99598 TSNAX 74.9 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P12956 XRCC6 47.9 III Nucleoplasm NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P61978 HNRNPK 42.6 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q8IWX8 CHERP 23.2 II NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P52272 HNRNPM 46.9 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9P258 RCC2 44.9 III NMF result: no prediction, SAFE result: no prediction 1 1
O00422 SAP18 63.4 IV Cytosol;Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P49750 YLPM1 44.9 III Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P38919 EIF4A3 67.1 V Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O15042 U2SURP 33.1 II Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q15366 PCBP2 48.9 III Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
O95793 STAU1 111.0 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q13595 TRA2A 42.2 II Nucleoli;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
Q16630 CPSF6 33.9 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q15427 SF3B4 38.3 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q6NZY4 ZCCHC8 40.2 II Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: - 1 1
P52597 HNRNPF 42.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q08211 DHX9 50.2 III Nucleus NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14004 CDK13 37.1 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q12874 SF3A3 37.2 II Nucleoplasm NMF result: chromatin, SAFE result: splicing speckles, nucleolus 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q13427 PPIG 53.4 III Nuclear speckles NMF result: nuclear body, SAFE result: spliceosomal complex II 1 1
O60506 SYNCRIP 71.4 V Cytosol;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles 1 1
Q9NVP1 DDX18 49.1 III Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
Q9Y388 RBMX2 39.8 II Nuclear membrane;Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q13838 DDX39B 67.1 V Nuclear speckles NMF result: nuclear body, SAFE result: no prediction 1 1
Q8IYB3 SRRM1 39.4 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
O43390 HNRNPR 48.0 III Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1