PSPC1
| UniProt Accession | Q8WXF1 UniProt 🔗 |
|---|---|
| Synonyms | PSP1 |
| UniProt protein names | Paraspeckle component 1;Paraspeckle protein 1 |
| Peak binding time (min) | 44.9 |
| Cluster | II |
| Cluster membership (corr) | 0.998 |
| Peak broadness (1 / std of log2 intensities) | 0.92 |
| Cluster expected from GO | II |
| Subcellular localization (Human Protein Atlas) | Nucleoli fibrillar center;Nucleoplasm |
| Subcellular localization (Human Cell Map) | NMF result: nuclear body, SAFE result: paraspeckles |
| RMSE (expected - observed) | 0.13 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of PSPC1 in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q15233 | NONO | 42.9 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 2 | 4 |
| P26368 | U2AF2 | 37.3 | II | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: - | 2 | 2 |
| P12956 | XRCC6 | 47.9 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q15717 | ELAVL1 | 46.3 | III | Cytosol;Nucleoli;Nucleus | NMF result: miscellaneous, SAFE result: paraspeckles | 1 | 1 |
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9H0D6 | XRN2 | 41.9 | II | Nucleoli;Nucleus | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q86VM9 | ZC3H18 | 39.6 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| O43809 | NUDT21 | 41.6 | II | Nuclear bodies | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| O14776 | TCERG1 | 40.9 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |
| Q15056 | EIF4H | 115.6 | VI | Cytosol;Nuclear bodies;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - | 1 | 1 |
| Q96I24 | FUBP3 | 51.8 | III | Cytosol;Nucleoplasm | NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: paraspeckles | 1 | 1 |
| P23246 | SFPQ | 45.2 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P49750 | YLPM1 | 44.9 | III | Nuclear speckles;Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q92879 | CELF1 | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P35637 | FUS | 37.8 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q8TAD8 | SNIP1 | 40.9 | II | Cytosol;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9H9G7 | AGO3 | 91.6 | VI | Cytoplasmic bodies;Nucleoplasm | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |