EIF4B


UniProt Accession P23588 UniProt 🔗
Synonyms
UniProt protein names Eukaryotic translation initiation factor 4B
Peak binding time (min) 213.8
Cluster VII
Cluster membership (corr) 0.999
Peak broadness (1 / std of log2 intensities) 1.26
Cluster expected from GO VI
Subcellular localization (Human Protein Atlas) Cytosol
Subcellular localization (Human Cell Map) NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule
RMSE (expected - observed) 0.37
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of EIF4B in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P11940 PABPC1 124.3 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 3
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 3 2
Q04637 EIF4G1 105.0 VI Cytosol NMF result: no prediction, SAFE result: no prediction 2 3
P38919 EIF4A3 67.1 V Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
P60842 EIF4A1 96.8 VI Cytosol NMF result: no prediction, SAFE result: no prediction 2 2
P33240 CSTF2 23.7 II Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 2
Q5TC82 RC3H1 62.0 IV Cytosol;Plasma membrane NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 2
Q15637 SF1 40.9 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q9Y3I0 RTCB 54.9 IV Cytosol;Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: - 1 1
Q92945 KHSRP 37.0 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
O15371 EIF3D 208.1 VII Cytosol NMF result: miscellaneous, SAFE result: - 1 1
Q9Y262 EIF3L 193.3 VII Nucleoli;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
Q92499 DDX1 74.7 V Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q9UIF9 BAZ2A 49.2 III Nuclear speckles NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q13242 SRSF9 44.3 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q15717 ELAVL1 46.3 III Cytosol;Nucleoli;Nucleus NMF result: miscellaneous, SAFE result: paraspeckles 1 1
Q13283 G3BP1 220.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P62314 SNRPD1 54.6 IV NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q14103 HNRNPD 43.1 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P31943 HNRNPH1 40.8 II Cytosol;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q8IXT5 RBM12B 48.7 III Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P61326 MAGOH 70.2 V Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
O75821 EIF3G 105.9 VI Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
O15372 EIF3H 64.3 IV Cytosol NMF result: centrosome, SAFE result: - 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
P38159 RBMX 44.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P11142 HSPA8 45.1 III Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 1
Q00839 HNRNPU 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
P78344 EIF4G2 200.0 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9H9G7 AGO3 91.6 VI Cytoplasmic bodies;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
P84103 SRSF3 43.0 II Nucleoplasm NMF result: nuclear body, SAFE result: no prediction 1 1