EIF4G2


UniProt Accession P78344 UniProt 🔗
Synonyms DAP5, OK/SW-cl.75
UniProt protein names Eukaryotic translation initiation factor 4 gamma 2;
Death-associated protein 5;
p97
Peak binding time (min) 200.0
Cluster VII
Cluster membership (corr) 0.991
Peak broadness (1 / std of log2 intensities) 2.08
Cluster expected from GO VII
Subcellular localization (Human Protein Atlas) Cytosol
Subcellular localization (Human Cell Map) NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule
RMSE (expected - observed) 0.09
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics


Gene Ontology based expectation (GO 2021-09-01)


Protein interactors of EIF4G2 in mRNP (BioGRID)


Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
P60842 EIF4A1 96.8 VI Cytosol NMF result: no prediction, SAFE result: no prediction 4 4
P11021 HSPA5 48.9 III Cytosol NMF result: ER lumen, SAFE result: ER lumen 1 1
Q14152 EIF3A 198.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9Y5A9 YTHDF2 111.0 VI Cytoplasmic bodies;Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q13283 G3BP1 220.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
P06748 NPM1 56.1 IV Nucleoli;Nucleus NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q9GZT3 SLIRP 71.4 V Mitochondria NMF result: no prediction, SAFE result: no prediction 1 1
Q7Z739 YTHDF3 111.3 VI Cytosol;Nuclear membrane;Nuclear speckles NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q04637 EIF4G1 105.0 VI Cytosol NMF result: no prediction, SAFE result: no prediction 1 1
O00571 DDX3X 146.2 VII Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: no prediction 1 1
P23588 EIF4B 213.8 VII Cytosol NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 1 1
P11142 HSPA8 45.1 III Nucleoplasm;Vesicles NMF result: miscellaneous, SAFE result: no prediction 1 1
Q9BY77 POLDIP3 74.6 V Cytoplasmic bodies;Nuclear speckles NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q15056 EIF4H 115.6 VI Cytosol;Nuclear bodies;Nucleoplasm NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: - 1 1
Q9C0B0 UNK 88.4 VI Cytoplasmic bodies;Cytosol NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
Q7Z2W4 ZC3HAV1 211.8 VII Cytosol;Golgi apparatus NMF result: nuclear outer membrane-ER membrane network, SAFE result: nuclear outer membrane-ER membrane network 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1