PLEC
| UniProt Accession | Q15149 UniProt 🔗 |
|---|---|
| Synonyms | PLEC1 |
| UniProt protein names | Plectin;Hemidesmosomal protein 1;Plectin-1 |
| Peak binding time (min) | 59.3 |
| Cluster | V |
| Cluster membership (corr) | 0.977 |
| Peak broadness (1 / std of log2 intensities) | 2.75 |
| Cluster expected from GO | V |
| Subcellular localization (Human Protein Atlas) | Cytosol;Focal adhesion sites;Intermediate filaments |
| Subcellular localization (Human Cell Map) | NMF result: centrosome, SAFE result: centrosome enriched, P-body enriched |
| RMSE (expected - observed) | 0.03 |
| Link to current annotations (QuickGO) | QuickGO 🔗 |
mRNA binding dynamics
Gene Ontology based expectation (GO 2021-09-01)
Protein interactors of PLEC in mRNP (BioGRID)
| Master Protein UniProt | Gene Symbol | Peak binding time (min) | Cluster | Subcellular localization (Human Protein Atlas) | Subcellular localization (Human Cell Map) | Number of evidences (experiment types) | Number of evidences (publications) |
|---|---|---|---|---|---|---|---|
| Q69YN4 | VIRMA | 0.0 | I | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 2 | 1 |
| Q14146 | URB2 | 5.1 | I | Nucleoli | NMF result: nucleolus, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P78332 | RBM6 | 38.1 | II | Cytoplasmic bodies;Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9Y2W1 | THRAP3 | 37.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q92841 | DDX17 | 39.2 | II | Nuclear speckles | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q9BQG0 | MYBBP1A | 54.4 | IV | Nucleoli;Vesicles | NMF result: nucleolus, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| O96028 | NSD2 | 41.7 | III | Nucleus | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q07666 | KHDRBS1 | 43.0 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| P14866 | HNRNPL | 42.6 | II | Nucleoplasm | NMF result: nuclear body, SAFE result: paraspeckles | 1 | 1 |
| Q99459 | CDC5L | 49.2 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q13573 | SNW1 | 51.8 | III | Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q9NWH9 | SLTM | 42.7 | II | Nuclear bodies;Nucleoplasm | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| P29401 | TKT | 46.5 | III | Nucleoplasm | NMF result: chromatin, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q13595 | TRA2A | 42.2 | II | Nucleoli;Vesicles | NMF result: no prediction, SAFE result: no prediction | 1 | 1 |
| Q9UQ35 | SRRM2 | 42.5 | III | Nuclear speckles | NMF result: nuclear body, SAFE result: splicing speckles, nucleolus | 1 | 1 |
| Q53F19 | NCBP3 | 77.1 | V | Nuclear speckles | NMF result: nuclear body, SAFE result: chromatin, nucleoplasm | 1 | 1 |
| Q15029 | EFTUD2 | 45.5 | III | Cytosol;Nucleoplasm | NMF result: miscellaneous, SAFE result: spliceosomal complex I | 1 | 1 |