SF3B6

UniProt Accession Q9Y3B4 UniProt 🔗
Synonyms CGI-110, HSPC175, HT006, SAP14, SF3B14, SF3B14A
UniProt protein names Splicing factor 3B subunit 6;
Pre-mRNA branch site protein p14;
SF3b 14 kDa subunit;
Spliceosome-associated protein, 14-kDa;
Splicing factor 3b, subunit 6, 14kDa
Peak binding time (min) 36.0
Cluster II
Cluster membership (corr) 0.999
Peak broadness (1 / std of log2 intensities) 1.11
Cluster expected from GO III
Subcellular localization (Human Protein Atlas) Nucleoplasm
Subcellular localization (Human Cell Map) NMF result: no prediction, SAFE result: no prediction
RMSE (expected - observed) 0.29
Link to current annotations (QuickGO) QuickGO 🔗

mRNA binding dynamics

Gene Ontology based expectation (GO 2021-09-01)

Protein interactors of SF3B6 in mRNP (BioGRID)

Master Protein UniProt Gene Symbol Peak binding time (min) Cluster Subcellular localization (Human Protein Atlas) Subcellular localization (Human Cell Map) Number of evidences (experiment types) Number of evidences (publications)
O75533 SF3B1 40.9 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 5 7
Q15393 SF3B3 45.7 II Nucleoli;Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 2 3
Q86VM9 ZC3H18 39.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
P26368 U2AF2 37.3 II Nuclear speckles;Nucleoplasm NMF result: nuclear body, SAFE result: - 2 2
Q7RTV0 PHF5A 37.6 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 2 2
Q99459 CDC5L 49.2 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 2 2
Q15029 EFTUD2 45.5 III Cytosol;Nucleoplasm NMF result: miscellaneous, SAFE result: spliceosomal complex I 2 2
Q15428 SF3A2 31.3 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 2
Q15427 SF3B4 38.3 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 2
Q13435 SF3B2 37.6 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 2
Q05519 SRSF11 52.0 III Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q16629 SRSF7 42.8 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P62826 RAN 44.7 III NMF result: no prediction, SAFE result: no prediction 1 1
O43290 SART1 39.6 II Golgi apparatus;Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P18583 SON 43.3 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
P62314 SNRPD1 54.6 IV NMF result: nuclear body, SAFE result: spliceosomal complex I 1 1
Q12906 ILF3 48.8 III Mitochondria;Nucleoli;Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q13573 SNW1 51.8 III Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q8TAD8 SNIP1 40.9 II Cytosol;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q8IY81 FTSJ3 69.4 V Nucleoli NMF result: nucleolus, SAFE result: splicing speckles, nucleolus 1 1
Q13243 SRSF5 41.7 II Nucleoli;Nucleus NMF result: no prediction, SAFE result: no prediction 1 1
Q13595 TRA2A 42.2 II Nucleoli;Vesicles NMF result: no prediction, SAFE result: no prediction 1 1
P11387 TOP1 48.2 III Nucleoli fibrillar center;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1
Q69YN4 VIRMA 0.0 I Nuclear bodies;Nucleoplasm NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q9Y2W1 THRAP3 37.2 II Nuclear speckles NMF result: nuclear body, SAFE result: splicing speckles, nucleolus 1 1
Q12986 NFX1 77.5 V Cytosol;Nucleus NMF result: cytoplasmic ribonucleoprotein granule, SAFE result: cytoplasmic ribonucleoprotein granule 1 1
Q9UHX1 PUF60 35.4 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
P09651 HNRNPA1 43.1 II Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q4G0J3 LARP7 54.3 IV Cytosol;Nucleoplasm NMF result: nucleolus, SAFE result: paraspeckles 1 1
O43143 DHX15 35.8 II Nuclear speckles NMF result: no prediction, SAFE result: no prediction 1 1
P38159 RBMX 44.4 II Nucleoplasm NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q5BKZ1 ZNF326 44.1 II Golgi apparatus;Nucleoplasm;Vesicles NMF result: nuclear body, SAFE result: paraspeckles 1 1
Q15424 SAFB 45.0 II Nucleoplasm NMF result: nuclear body, SAFE result: chromatin, nucleoplasm 1 1
Q14839 CHD4 61.8 III Nucleus NMF result: chromatin, SAFE result: chromatin, nucleoplasm 1 1
P12270 TPR 53.6 IV Nuclear membrane NMF result: no prediction, SAFE result: no prediction 1 1
Q9H9G7 AGO3 91.6 VI Cytoplasmic bodies;Nucleoplasm NMF result: no prediction, SAFE result: no prediction 1 1
Q12873 CHD3 52.4 IV Microtubule organizing center;Nucleoli;Nucleus NMF result: nucleoplasm, SAFE result: chromatin, nucleoplasm 1 1